OSLAM syndrome

OSLAM syndrome is a rare condition that includes the occurrence of osteosarcoma (a type of bone cancer), characteristic limb anomalies, and blood cell differences. People with this condition may have unusual hand and foot features such as clinodactyly (curved fingers), brachymesophalangy, bilateral radioulnar synostosis (fusion of the forearm bones), and the absence of one digital ray in the foot. In addition to these physical features, individuals with OSLAM syndrome have a type of red blood cell change known as macrocytosis without anemia. This means that while the red cells are larger than normal, they do not cause anemia. The condition is recognized and categorized in medical databases like OMIM, Orphanet, and GARD.

The symptoms of OSLAM syndrome include the development of osteosarcoma, limb anomalies such as clinodactyly with brachymesophalangy, bilateral radioulnar synostosis, and the absence of one digital ray in the foot. There is also the presence of red cell macrocytosis without anemia.

Information about causes is currently limited for this condition.

Information about treatment is currently limited for this condition.

Information about prognosis is currently limited for this condition.

Information about current research and future directions is currently limited for this condition.