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Features include always present findings: Premature ovarian insufficiency, Elevated circulating luteinizing hormone level, Elevated circulating follicle stimulating hormone level, and Delayed puberty and others; and common findings: Streak ovary and Hypoplasia of the ovary.
Organ System | Phenotype Count | Example Features |
|---|---|---|
Lab test results | 2 | Elevated circulating luteinizing hormone level, Elevated circulating follicle stimulating hormone level |
ZSWIM7 function has not been fully characterized.
Ovarian dysgenesis 10 is associated with mutations in the ZSWIM7 gene on chromosome 17.
Genetic testing for ZSWIM7 is available. Testing is considered confirmatory for diagnosis.
Biomarker and diagnostic research for ovarian dysgenesis 10 has been reported in the published literature.
Phenotype severity distribution: 6 always present features, 2 common features.
No clinical trials have been registered for ovarian dysgenesis 10.
71 publications have been identified in PubMed for ovarian dysgenesis 10. Research spans Case Report / Case Series (32%), Basic Science / Preclinical (18%), and Review / Meta-Analysis (15%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 23 | 32% |
Data assembled from 5 of 12 sources · Last updated Sep 20, 2026, 12:13 AM UTC
Online Mendelian Inheritance in Man
Hormones | 2 | Delayed puberty, Primary amenorrhea |
13 |
18% |
Research summaries | 11 | 15% |
Clinical study results | 10 | 14% |
Disease patterns and progression | 9 | 13% |
Testing and diagnosis research | 3 | 4% |
New treatment approaches | 2 | 3% |
Tao X (2026). [PMID: 41790662](https://pubmed.ncbi.nlm.nih.gov/41790662/). *Medicine*. [Case Report / Case Series]
Li HC (2026). [PMID: 42036198](https://pubmed.ncbi.nlm.nih.gov/42036198/). *Taiwan J Obstet Gynecol*. [Case Report / Case Series]
Odunvbun WO (2026). [PMID: 42202883](https://pubmed.ncbi.nlm.nih.gov/42202883/). *Afr J Reprod Health*. [Review / Meta-Analysis]
Dowlut-McElroy T (2026). [PMID: 41043543](https://pubmed.ncbi.nlm.nih.gov/41043543/). *Journal of pediatric and adolescent gynecology*. [Clinical Trial Publication]
Gawron I (2026). [PMID: 41045827](https://pubmed.ncbi.nlm.nih.gov/41045827/). *Arch Med Res*. [Epidemiology / Natural History]
Shuai X (2026). [PMID: 42165018](https://pubmed.ncbi.nlm.nih.gov/42165018/). *Front Endocrinol (Lausanne)*. [Case Report / Case Series]
Zhang Q (2026). [PMID: 41918383](https://pubmed.ncbi.nlm.nih.gov/41918383/). *Zhonghua Yi Xue Yi Chuan Xue Za Zhi*. [Case Report / Case Series]
Liang J (2026). [PMID: 41317609](https://pubmed.ncbi.nlm.nih.gov/41317609/). *European journal of obstetrics, gynecology, and reproductive biology*. [Case Report / Case Series]
Sage A (2026). [PMID: 41535243](https://pubmed.ncbi.nlm.nih.gov/41535243/). *Human reproduction (Oxford, England)*. [Review / Meta-Analysis]
Dong Y (2026). [PMID: 41555764](https://pubmed.ncbi.nlm.nih.gov/41555764/). *Am J Med Genet A*. [Review / Meta-Analysis]