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ovarian gynandroblastoma - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

ovarian gynandroblastoma

MONDO:0020540

Also known as:Gynandroblastoma of ovaryGynandroblastoma of the ovaryGynandroblastoma

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Overview

A rare neoplasm arising from the ovary. Although it may occur at any age, it is more often seen in young females. Morphologically, it is characterized by a mixture of two cellular populations: well differentiated Sertoli cells and granulosa cells, with the latter constituting at least ten percent of the neoplasm. The vast majority of cases are stage I lesions at presentation and produce either estrogenic or androgenic manifestations. Although it may present as a massive ovarian tumor, it usually follows a benign clinical course. Very rare case reports of testicular lesions morphologically resembling gynandroblastomas are in fact variants of juvenile granulose cell tumor, or Sertoli cell tumor, or a combination of both.

Clinical Trials1 registered

ResearchLimited published research (8 articles)

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

1 clinical trial registered. Interventions under study include other interventions. Research is primarily sponsored by academic and government institutions.

9 publications have been identified in PubMed for ovarian gynandroblastoma. Research spans Case Report / Case Series (63%), Review / Meta-Analysis (25%), and Basic Science / Preclinical (13%).

Recent Publications

Kim HS (2026). [PMID: 41243833](https://pubmed.ncbi.nlm.nih.gov/41243833/). *Adv Anat Pathol*. [Review / Meta-Analysis]
Lucas E (2026). [PMID: 41021597](https://pubmed.ncbi.nlm.nih.gov/41021597/). *Int J Surg Pathol*. [Review / Meta-Analysis]
Hirata T (2025). [PMID: 40492655](https://pubmed.ncbi.nlm.nih.gov/40492655/). *Pediatr Int*. [Case Report / Case Series]
Ray LJ (2025). [PMID: 40326456](https://pubmed.ncbi.nlm.nih.gov/40326456/). *Am J Surg Pathol*. [Basic Science / Preclinical]
Limbachiya D (2025). [PMID: 40390890](https://pubmed.ncbi.nlm.nih.gov/40390890/). *J Obstet Gynaecol India*. [Case Report / Case Series]

Data assembled from 4 of 12 sources · Last updated Sep 20, 2026, 1:36 AM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:99914

GARD

Genetic and Rare Diseases Info Center

GARD:9665

Questions for Your Care Team

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ovarian gynandroblastoma

Overview

Research Landscape

Recent Publications

Medical References

External Resources

Orphanet

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team