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Acute suppurative inflammation of the inner eye with necrosis of the sclera (and sometimes the cornea) and extension of the inflammation into the orbit. Pain may be severe and the globe may rupture. In endophthalmitis the globe does not rupture.
No clinical trials have been registered for panophthalmitis.
38 publications have been identified in PubMed for panophthalmitis. Research spans Case Report / Case Series (71%), Review / Meta-Analysis (9%), and Basic Science / Preclinical (9%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 25 | 71% |
Research summaries | 3 | 9% |
Laboratory research | 3 | 9% |
Disease patterns and progression | 3 | 9% |
Other research | 1 |
Data assembled from 2 of 12 sources · Last updated Sep 19, 2026, 12:59 PM UTC
Jaffer A (2026). [PMID: 42158558](https://pubmed.ncbi.nlm.nih.gov/42158558/). *Am J Ophthalmol Case Rep*. [Case Report / Case Series]
Vaishnav B (2026). [PMID: 40587085](https://pubmed.ncbi.nlm.nih.gov/40587085/). *Ann Afr Med*. [Case Report / Case Series]
Louca M (2026). [PMID: 41700124](https://pubmed.ncbi.nlm.nih.gov/41700124/). *Orbit*. [Case Report / Case Series]
Assenmacher CA (2026). [PMID: 41562140](https://pubmed.ncbi.nlm.nih.gov/41562140/). *J Vet Diagn Invest*. [Case Report / Case Series]
Uner OE (2026). [PMID: 41698218](https://pubmed.ncbi.nlm.nih.gov/41698218/). *Retin Cases Brief Rep*. [Case Report / Case Series]
Anil A (2026). [PMID: 41962662](https://pubmed.ncbi.nlm.nih.gov/41962662/). *Indian J Med Microbiol*. [Case Report / Case Series]
Silva DN (2026). [PMID: 41208587](https://pubmed.ncbi.nlm.nih.gov/41208587/). *Vet Ophthalmol*. [Basic Science / Preclinical]
Jayagandan S (2026). [PMID: 41858517](https://pubmed.ncbi.nlm.nih.gov/41858517/). *IDCases*. [Case Report / Case Series]
Woock AE (2026). [PMID: 41765170](https://pubmed.ncbi.nlm.nih.gov/41765170/). *J AAPOS*. [Case Report / Case Series]
Alothman L (2025). [PMID: 40656890](https://pubmed.ncbi.nlm.nih.gov/40656890/). *Int Med Case Rep J*. [Case Report / Case Series]
AI-curated news mentioning panophthalmitis
Updated Feb 17, 2026
A recent study highlights a case of secondary orbital abscess caused by hypervirulent Klebsiella pneumoniae leading to panophthalmitis and scleral necrosis. This research contributes to the understanding of rare infectious complications in ophthalmology.