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paramedian nasal cleft - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

paramedian nasal cleft

MONDO:0015414

Also known as:Tessier number 1 cleftalar cleftalar rim cleft

Overview

Paramedian nasal cleft is a rare developmental defect during embryogenesis characterized by a unilateral or bilateral coloboma of the nose, ranging in severity from a small notch, resulting in minor deviation of the nasal septum, to variable-sized clefts of the nasal ala which may be associated with small cysts or sinuses in the nasal midline. Defect may be isolated or may occur in association with cleft lip and/or other craniofacial anomalies (e.g. hypertelorism, broadening of nasal root, midline cleft). Dorsum and apex of nose are usually well preserved.

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

No clinical trials have been registered for paramedian nasal cleft.

12 publications have been identified in PubMed for paramedian nasal cleft. Research spans Case Report / Case Series (55%), Clinical Trial Publication (27%), and Basic Science / Preclinical (9%).

Research Type	Count	% of Total
Patient case studies	6	55%

Data assembled from 3 of 12 sources · Last updated Sep 20, 2026, 3:02 PM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:141242

GARD

Genetic and Rare Diseases Info Center

GARD:16973

Questions for Your Care Team

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paramedian nasal cleft

Overview

Research Landscape

Medical References

External Resources

Orphanet

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

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