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Paraparetic variant of Guillain-Barré syndrome is a rare variant of Guillain-Barré syndrome characterized by isolated leg weakness, areflexia and radicular leg pain that may simulate a cauda equina or spinal cord syndrome. The arms, ocular, facial, and oropharyngeal muscles are spared, and sphincteric function is normal.
Estimated prevalence: Unknown (Unknown prevalence).
No clinical trials have been registered for paraparetic variant of Guillain-Barre syndrome.
3 publications have been identified in PubMed for paraparetic variant of Guillain-Barre syndrome. Research spans Case Report / Case Series (67%) and Epidemiology / Natural History (33%).
Liang Y (2025). [PMID: 40826773](https://pubmed.ncbi.nlm.nih.gov/40826773/). *Medicine (Baltimore)*. [Case Report / Case Series]
Garvayo Fernández F (2025). [PMID: 40412654](https://pubmed.ncbi.nlm.nih.gov/40412654/). *Rev Esp Anestesiol Reanim (Engl Ed)*. [Case Report / Case Series]
Maini DK (2025). [PMID: 40726664](https://pubmed.ncbi.nlm.nih.gov/40726664/). *J Family Med Prim Care*. [Epidemiology / Natural History]
Data assembled from 3 of 12 sources · Last updated Sep 20, 2026, 9:49 PM UTC
European rare disease database
Genetic and Rare Diseases Info Center