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patent ductus arteriosus 3 (PDA3) - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

patent ductus arteriosus 3

MONDO:0024266

Also known as:PDA3PRDM6 patent ductus arteriosuspatent ductus arteriosus caused by mutation in PRDM6

Overview

Any patent ductus arteriosus in which the cause of the disease is a mutation in the PRDM6 gene.

GeneticsAutosomal dominant · PRDM6 (chr 5)

OnsetCONGENITAL

Clinical Presentation

Features include: Patent ductus arteriosus.

Age of onset: at birth.

Explore clinical features

Genetic Landscape

PRDM6 function has not been fully characterized.

Patent ductus arteriosus 3 is associated with mutations in the PRDM6 gene on chromosome 5.

Diagnosis

Genetic testing for PRDM6 is available. Testing is considered confirmatory for diagnosis.

Biomarker and diagnostic research for patent ductus arteriosus 3 has been reported in the published literature.

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

No clinical trials have been registered for patent ductus arteriosus 3.

201 publications have been identified in PubMed for patent ductus arteriosus 3. Kisho has analyzed 108 by research type. Research spans Clinical Trial Publication (41%), Epidemiology / Natural History (28%), and Review / Meta-Analysis (16%).

Research Type	Count	% of Total
Clinical study results	44	41%

Data assembled from 5 of 12 sources · Last updated Sep 18, 2026, 6:03 PM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

OMIM

Online Mendelian Inheritance in Man

OMIM:617039

GARD

Genetic and Rare Diseases Info Center

GARD:18490

Questions for Your Care Team

→Should I pursue genetic testing for PRDM6, and what would the results mean for my family?
→Are there specialists or centers of excellence for this condition in my area?
→Is there a patient registry I should consider joining?

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patent ductus arteriosus 3

Overview

Clinical Presentation

Explore clinical features

Genetic Landscape

Diagnosis

Research Landscape

Medical References

External Resources

OMIM

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

Recent Publications