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Pfeiffer syndrome type 2 (PS2) is a frequent and severe type of Pfeiffer syndrome (PS), characterized by cloverleaf skull, severe associated functional disorders, and hand/foot and elbow/knee abnormalities.
Estimated prevalence: Unknown (Unknown prevalence).
No clinical trials have been registered for Pfeiffer syndrome type 2.
6 publications have been identified in PubMed for Pfeiffer syndrome type 2. Research spans Case Report / Case Series (50%), Epidemiology / Natural History (33%), and Basic Science / Preclinical (17%).
Onur H (2026). [PMID: 42084887](https://pubmed.ncbi.nlm.nih.gov/42084887/). *Turk Arch Pediatr*. [Basic Science / Preclinical]
Cuperus IE (2026). [PMID: 42024012](https://pubmed.ncbi.nlm.nih.gov/42024012/). *Plast Reconstr Surg*. [Epidemiology / Natural History]
Gulhote DA (2026). [PMID: 41911563](https://pubmed.ncbi.nlm.nih.gov/41911563/). *J Craniofac Surg*. [Epidemiology / Natural History]
Sharma P (2025). [PMID: 40390968](https://pubmed.ncbi.nlm.nih.gov/40390968/). *J Obstet Gynaecol India*. [Case Report / Case Series]
Inoue E (2024). [PMID: 39503147](https://pubmed.ncbi.nlm.nih.gov/39503147/). *Anesth Prog*. [Case Report / Case Series]
Data assembled from 3 of 12 sources · Last updated Sep 19, 2026, 5:35 AM UTC
European rare disease database
Genetic and Rare Diseases Info Center
Common questions about Pfeiffer syndrome type 2