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pityriasis rubra pilaris - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

pityriasis rubra pilaris

MONDO:0100017

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Overview

A group of skin conditions that cause constant inflammation and scaling of the skin. People with PRP have reddish, scaly patches that may occur everywhere on the body, or only on certain areas. Some people with PRP also develop thickened skin on the underside of the hands and feet (palmoplantar keratoderma), various nail abnormalities, and/or thinning of the hair. There are several types of PRP classified by age when symptoms begin, body areas involved, and whether other conditions are present. This condition occurs in adults (adult onset PRP) as well as children (juvenile onset PRP).

Clinical Trials2 registered

Diagnosis

Biomarker and diagnostic research for pityriasis rubra pilaris has been reported in the published literature.

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

2 clinical trials registered. Interventions under study include drug therapy. Pipeline includes 1 PHASE4, 1 PHASE2. Research is primarily sponsored by academic and government institutions.

108 publications have been identified in PubMed for pityriasis rubra pilaris. Research spans Case Report / Case Series (46%), Review / Meta-Analysis (22%), and Other (18%).

Research Type	Count	% of Total
Patient case studies	48	46%

Data assembled from 3 of 12 sources · Last updated Sep 19, 2026, 6:46 AM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

GARD

Genetic and Rare Diseases Info Center

GARD:7401

Questions for Your Care Team

→Are any of the 2 active clinical trials a good fit for my situation?
→Are there specialists or centers of excellence for this condition in my area?
→Is there a patient registry I should consider joining?

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pityriasis rubra pilaris

Overview

Diagnosis

Research Landscape

Medical References

External Resources

GARD

Subtypes

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

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