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Biomarker and diagnostic research for PLG-related hereditary angioedema with normal C1inh has been reported in the published literature.
Estimated prevalence: <1 in 1,000,000 (VERY_RARE).
No clinical trials have been registered for PLG-related hereditary angioedema with normal C1inh.
9 publications have been identified in PubMed for PLG-related hereditary angioedema with normal C1inh. Research spans Review / Meta-Analysis (33%), Diagnostic / Biomarker (22%), and Clinical Trial Publication (22%).
Bocquet A (2025). [PMID: 41331604](https://pubmed.ncbi.nlm.nih.gov/41331604/). *Orphanet J Rare Dis*. [Case Report / Case Series]
Magerl M (2025). [PMID: 40276547](https://pubmed.ncbi.nlm.nih.gov/40276547/). *J Allergy Clin Immunol Glob*. [Epidemiology / Natural History]
Zuraw BL (2025). [PMID: 40053270](https://pubmed.ncbi.nlm.nih.gov/40053270/). *Clin Rev Allergy Immunol*. [Review / Meta-Analysis]
Aman Ur Rahman W (2025). [PMID: 40711100](https://pubmed.ncbi.nlm.nih.gov/40711100/). *Sports (Basel)*. [Review / Meta-Analysis]
Cohn DM (2025). [PMID: 40876763](https://pubmed.ncbi.nlm.nih.gov/40876763/). *J Allergy Clin Immunol*. [Clinical Trial Publication]
Data assembled from 3 of 12 sources · Last updated Sep 20, 2026, 5:33 PM UTC
European rare disease database
Genetic and Rare Diseases Info Center
Common questions about PLG-related hereditary angioedema with normal C1inh
Zwiener R (2025). [PMID: 39991622](https://pubmed.ncbi.nlm.nih.gov/39991622/). *J Allergy Clin Immunol Glob*. [Diagnostic / Biomarker]
Garcia R (2025). [PMID: 40042097](https://pubmed.ncbi.nlm.nih.gov/40042097/). *CPT Pharmacometrics Syst Pharmacol*. [Clinical Trial Publication]
Laney DA (2025). [PMID: 40201039](https://pubmed.ncbi.nlm.nih.gov/40201039/). *J Allergy Clin Immunol Glob*. [Diagnostic / Biomarker]
Pagnier A (2024). [PMID: 39655944](https://pubmed.ncbi.nlm.nih.gov/39655944/). *Pediatr Allergy Immunol*. [Review / Meta-Analysis]