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A non-severe combined immunodeficiency due to polymerase delta deficiency in which the cause of the disease is a variation in the POLD2 gene.
Biomarker and diagnostic research for POLD2-related combined immunodeficiency has been reported in the published literature.
No clinical trials have been registered for POLD2-related combined immunodeficiency.
210 publications have been identified in PubMed for POLD2-related combined immunodeficiency. Research spans Review / Meta-Analysis (35%), Case Report / Case Series (20%), and Basic Science / Preclinical (14%).
Research Type | Count | % of Total |
|---|---|---|
Research summaries | 73 | 35% |
Data assembled from 2 of 12 sources · Last updated Sep 18, 2026, 3:22 AM UTC
Common questions about POLD2-related combined immunodeficiency
Patient case studies
41 |
20% |
Laboratory research | 30 | 14% |
Disease patterns and progression | 27 | 13% |
Testing and diagnosis research | 18 | 9% |
Clinical study results | 12 | 6% |
New treatment approaches | 8 | 4% |
Other research | 1 | 0% |
Hartling HJ (2026). [PMID: 41968810](https://pubmed.ncbi.nlm.nih.gov/41968810/). *Ugeskr Laeger*. [Review / Meta-Analysis]
Soomann M (2026). [PMID: 41177434](https://pubmed.ncbi.nlm.nih.gov/41177434/). *The journal of allergy and clinical immunology. In practice*. [Epidemiology / Natural History]
Laberko A (2026). [PMID: 41786511](https://pubmed.ncbi.nlm.nih.gov/41786511/). *Expert Rev Clin Immunol*. [Review / Meta-Analysis]
Maccari ME (2026). [PMID: 41177421](https://pubmed.ncbi.nlm.nih.gov/41177421/). *Clin Immunol*. [Epidemiology / Natural History]
Torres-Valle A (2026). [PMID: 41176068](https://pubmed.ncbi.nlm.nih.gov/41176068/). *The Journal of allergy and clinical immunology*. [Diagnostic / Biomarker]
Miller RZ (2026). [PMID: 41451822](https://pubmed.ncbi.nlm.nih.gov/41451822/). *Current opinion in allergy and clinical immunology*. [Review / Meta-Analysis]
Woessner NM (2026). [PMID: 41482192](https://pubmed.ncbi.nlm.nih.gov/41482192/). *Immunology letters*. [Review / Meta-Analysis]
Jeong PS (2026). [PMID: 40280544](https://pubmed.ncbi.nlm.nih.gov/40280544/). *Journal of advanced research*. [Basic Science / Preclinical]
Yue J (2026). [PMID: 41147740](https://pubmed.ncbi.nlm.nih.gov/41147740/). *Arthritis & rheumatology (Hoboken, N.J.)*. [Diagnostic / Biomarker]
Sahbani F (2026). [PMID: 41834055](https://pubmed.ncbi.nlm.nih.gov/41834055/). *J Med Case Rep*. [Case Report / Case Series]