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A chordoma that is characterized by loss of SMARCB1 expression and that is composed of sheets or nests of malignant epithelioid cells with abundant eosinophilic cytoplasm.
Biomarker and diagnostic research for poorly differentiated chordoma has been reported in the published literature.
1 clinical trial registered. Interventions under study include other interventions, procedural interventions, and biologic therapy. Pipeline includes 1 PHASE1. Research is primarily sponsored by academic and government institutions.
16 publications have been identified in PubMed for poorly differentiated chordoma. Research spans Case Report / Case Series (38%), Basic Science / Preclinical (25%), and Epidemiology / Natural History (13%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 6 |
Data assembled from 3 of 12 sources · Last updated Sep 19, 2026, 8:51 AM UTC
Laboratory research | 4 | 25% |
Disease patterns and progression | 2 | 13% |
Other research | 1 | 6% |
Testing and diagnosis research | 1 | 6% |
Research summaries | 1 | 6% |
Clinical study results | 1 | 6% |
Xing J (2026). [PMID: 42165926](https://pubmed.ncbi.nlm.nih.gov/42165926/). *Discov Oncol*. [Epidemiology / Natural History]
Gounder M (2026). [PMID: 41882006](https://pubmed.ncbi.nlm.nih.gov/41882006/). *Nat Commun*. [Clinical Trial Publication]
Furuta T (2026). [PMID: 41603920](https://pubmed.ncbi.nlm.nih.gov/41603920/). *Pediatr Radiol*. [Other]
O'Connor P (2025). [PMID: 39533889](https://pubmed.ncbi.nlm.nih.gov/39533889/). *International journal of surgical pathology*. [Case Report / Case Series]
Sande WJ (2025). [PMID: 39577663](https://pubmed.ncbi.nlm.nih.gov/39577663/). *Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc*. [Basic Science / Preclinical]
Baluszek S (2025). [PMID: 41420192](https://pubmed.ncbi.nlm.nih.gov/41420192/). *Acta neuropathologica communications*. [Basic Science / Preclinical]
Laxpati N (2025). [PMID: 39705702](https://pubmed.ncbi.nlm.nih.gov/39705702/). *Journal of neurosurgery. Pediatrics*. [Case Report / Case Series]
Panda AK (2025). [PMID: 40696095](https://pubmed.ncbi.nlm.nih.gov/40696095/). *Neuropathology : official journal of the Japanese Society of Neuropathology*. [Case Report / Case Series]
Terzioğlu HG (2025). [PMID: 39533895](https://pubmed.ncbi.nlm.nih.gov/39533895/). *International journal of surgical pathology*. [Case Report / Case Series]
Smith HL (2025). [PMID: 41374972](https://pubmed.ncbi.nlm.nih.gov/41374972/). *Cancers*. [Review / Meta-Analysis]