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posterior polymorphous corneal dystrophy (PPCD) - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

posterior polymorphous corneal dystrophy

MONDO:0020364

Also known as:PPCDSchlichting dystrophycorneal dystrophy, posterior polymorphous

Find Clinical TrialsTrials

Overview

Posterior polymorphous corneal dystrophy (PPCD) is a rare mild subtype of posterior corneal dystrophy characterized by small aggregates of apparent vesicles bordered by a gray haze at the level of Descemet membrane, generally with no effect on vision.

OnsetCONGENITAL, INFANTILE

Clinical Trials1 registered · 1 recruiting

Diagnosis

Biomarker and diagnostic research for posterior polymorphous corneal dystrophy has been reported in the published literature.

Prognosis

Estimated prevalence: Unknown (Unknown prevalence).

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

1 clinical trial registered, 1 recruiting. Interventions under study include other interventions and gene therapy. Research is primarily sponsored by academic and government institutions.

17 publications have been identified in PubMed for posterior polymorphous corneal dystrophy. Research spans Case Report / Case Series (47%), Basic Science / Preclinical (20%), and Diagnostic / Biomarker (13%).

Research Type	Count	% of Total
Patient case studies	7

Data assembled from 4 of 12 sources · Last updated Sep 19, 2026, 7:47 AM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:98973

GARD

Genetic and Rare Diseases Info Center

GARD:16882

Questions for Your Care Team

→Are any of the 1 active clinical trial a good fit for my situation?
→Are there specialists or centers of excellence for this condition in my area?
→Is there a patient registry I should consider joining?

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posterior polymorphous corneal dystrophy

Overview

Diagnosis

Prognosis

Research Landscape

Medical References

External Resources

Orphanet

GARD

Subtypes

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

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