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postmenopausal osteoporosis - Clinical Profile, Treatments & Trials | Kisho | Kisho

Rare Disease

postmenopausal osteoporosis

MONDO:0008159

Also known as:bone mineral density quantitative trait locusosteoporosis, postmenopausal

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Overview

Metabolic disorder associated with fractures of the femoral neck, vertebrae, and distal forearm. It occurs commonly in women within 15-20 years after menopause, and is caused by factors associated with menopause including estrogen deficiency.

Treatments9 FDA approved

Clinical Trials38 registered · 16 recruiting

Diagnosis

Biomarker and diagnostic research for postmenopausal osteoporosis has been reported in the published literature.

Treatment

Compiled from FDA-approved drug records, orphan drug designations, and FDA Adverse Event Reporting System (FAERS) safety data. GeneReviews management guidance is included where available.

8 FDA-approved treatments are available for postmenopausal osteoporosis, including ESTROGENS, CONJUGATED (PREMARIN, approved 1942), RISEDRONATE SODIUM (ACTONEL, approved 1998), and ESTRADIOL AND LEVONORGESTREL (CLIMARA PRO, approved 2003).

Approved Therapies

Brand Name	Generic Name	Mechanism	Approved	Market Status

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

38 clinical trials registered, 16 recruiting. Interventions under study include drug therapy, other interventions, medical devices, and procedural interventions. Pipeline includes 12 PHASE4, 1 PHASE3, 4 PHASE2. Research is sponsored by a mix of industry and academic institutions.

NCT ID	Title	Phase	Sponsor	Status
[NCT06164795](https://clinicaltrials.gov/study/NCT06164795)

Data assembled from 4 of 12 sources · Last updated Sep 19, 2026, 6:53 PM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

Questions for Your Care Team

→What are the benefits and potential side effects of PREMARIN for managing postmenopausal osteoporosis?
→Are any of the 38 active clinical trials a good fit for my situation?
→Are there specialists or centers of excellence for this condition in my area?
→Is there a patient registry I should consider joining?

← Back to All Diseases

Research Type	Count	% of Total
Laboratory research	64	38%
Research summaries	51	30%
Disease patterns and progression	20	12%
New treatment approaches	15	9%
Clinical study results	14	8%
Testing and diagnosis research	5	3%

postmenopausal osteoporosis

Overview

Diagnosis

Treatment

Approved Therapies

Research Landscape

Medical References

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

Clinical Trials

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