Kisho is an information platform, not a medical provider. Nothing on this site constitutes medical advice, diagnosis, or treatment recommendations. All content is aggregated from publicly available sources (including ClinicalTrials.gov, PubMed, FDA.gov, and Orphanet) and is provided for informational purposes only. Clinical trial eligibility, treatment decisions, and any health-related actions should always be discussed with a qualified healthcare professional. Kisho does not endorse any specific therapy, organization, or clinical trial. Terms of use · Privacy policy
A hormonal disorder that occurs when the adrenal glands fail to release adequate amounts of glucocorticoids (cortisol), mineralocorticoids (aldosterone, 11-deoxycorticosterone), and androgens (dehydroepiandrosterone) to meet physiologic needs, despite release of ACTH from the pituitary.
Biomarker and diagnostic research for primary adrenal insufficiency has been reported in the published literature.
4 clinical trials registered. Interventions under study include other interventions and medical devices. Pipeline includes 3 NA. Research is primarily sponsored by academic and government institutions.
268 publications have been identified in PubMed for primary adrenal insufficiency. Kisho has analyzed 212 by research type. Research spans Case Report / Case Series (56%), Review / Meta-Analysis (21%), and Epidemiology / Natural History (8%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 118 |
Data assembled from 4 of 12 sources · Last updated Sep 17, 2026, 11:56 PM UTC
Program availability and eligibility requirements are set by each foundation. Contact them directly to learn more about your options.
Claim this page and your organization will be listed here for patients and families to find.
European rare disease database
Genetic and Rare Diseases Info Center
Research summaries | 44 | 21% |
Disease patterns and progression | 17 | 8% |
Laboratory research | 12 | 6% |
Clinical study results | 9 | 4% |
Testing and diagnosis research | 6 | 3% |
Other research | 3 | 1% |
New treatment approaches | 3 | 1% |
Meireles AR (2026). [PMID: 41756471](https://pubmed.ncbi.nlm.nih.gov/41756471/). *JCEM Case Rep*. [Case Report / Case Series]
Kucuka I (2026). [PMID: 41678364](https://pubmed.ncbi.nlm.nih.gov/41678364/). *J Clin Endocrinol Metab*. [Epidemiology / Natural History]
Colorado Franco LA (2026). [PMID: 42220732](https://pubmed.ncbi.nlm.nih.gov/42220732/). *Cureus*. [Case Report / Case Series]
Manna S (2026). [PMID: 41918595](https://pubmed.ncbi.nlm.nih.gov/41918595/). *Indian J Endocrinol Metab*. [Epidemiology / Natural History]
Acosta Bedón A (2026). [PMID: 41386740](https://pubmed.ncbi.nlm.nih.gov/41386740/). *Am J Med Genet A*. [Case Report / Case Series]
Talib AM (2026). [PMID: 42159516](https://pubmed.ncbi.nlm.nih.gov/42159516/). *JACC Case Rep*. [Case Report / Case Series]
Abadie J (2026). [PMID: 41964898](https://pubmed.ncbi.nlm.nih.gov/41964898/). *Lab Med*. [Case Report / Case Series]
Kumar G (2026). [PMID: 41935290](https://pubmed.ncbi.nlm.nih.gov/41935290/). *BMC Infect Dis*. [Case Report / Case Series]
Prete A (2026). [PMID: 41552007](https://pubmed.ncbi.nlm.nih.gov/41552007/). *EClinicalMedicine*. [Clinical Trial Publication]
Huang S (2026). [PMID: 42053005](https://pubmed.ncbi.nlm.nih.gov/42053005/). *Br J Hosp Med (Lond)*. [Case Report / Case Series]
AI-curated news mentioning primary adrenal insufficiency
Updated May 15, 2026
A recent observational cohort study highlights rare causes of pediatric primary adrenal insufficiency, providing valuable insights into this condition. The findings may inform future research and clinical approaches to diagnosis and treatment.
A case report highlights primary adrenal insufficiency in a patient with pseudo-neonatal adrenoleukodystrophy, contributing to the understanding of this rare condition. The findings may inform future research and clinical approaches to managing similar cases.