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primary amebic meningoencephalitis - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

primary amebic meningoencephalitis

MONDO:0000290

Also known as:Naegleria fowleri infectioninfections, Naegleria fowleri

Overview

A infectious disease involving the Naegleria fowleri.

TreatmentsNo approved treatments · 1 in pipeline

Diagnosis

Biomarker and diagnostic research for primary amebic meningoencephalitis has been reported in the published literature.

Treatment

Compiled from FDA-approved drug records, orphan drug designations, and FDA Adverse Event Reporting System (FAERS) safety data. GeneReviews management guidance is included where available.

No approved treatments are currently available for primary amebic meningoencephalitis. An additional 1 compound holds orphan drug designation.

Orphan Drug Designations

While no drugs are FDA-approved specifically for primary amebic meningoencephalitis, some of the following designated compounds may be used off-label in clinical practice. Treatment decisions should be made in consultation with a specialist familiar with this condition.

The following drugs have received orphan drug designation from the FDA for primary amebic meningoencephalitis. Orphan designation reflects regulatory interest and does not indicate approval for treatment.

Brand Name	Generic Name	Sponsor

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

No clinical trials have been registered for primary amebic meningoencephalitis.

120 publications have been identified in PubMed for primary amebic meningoencephalitis. Research spans Basic Science / Preclinical (23%), Case Report / Case Series (21%), and Epidemiology / Natural History (21%).

Research Type	Count	% of Total
Laboratory research	28	23%

Data assembled from 3 of 12 sources · Last updated Sep 20, 2026, 11:11 AM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

GARD

Genetic and Rare Diseases Info Center

GARD:9554

Questions for Your Care Team

→What is the current development status of corifungin, and when might it become available?
→Are there specialists or centers of excellence for this condition in my area?
→Is there a patient registry I should consider joining?

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Kisho

primary amebic meningoencephalitis

Overview

Diagnosis

Treatment

Orphan Drug Designations

Research Landscape

Medical References

External Resources

GARD

Questions for Your Care Team

Questions for Your Care Team

Clinical Trials

Recent Publications

Latest News & Developments

Primary amoebic meningoencephalitis: discovery and understanding of a novel disease.

Pharmacological Interventions in Primary Amoebic Meningoencephalitis: Clinical Challenges and Strategic Solutions.

primary amebic meningoencephalitis

Overview

Diagnosis

Treatment

Orphan Drug Designations

Research Landscape

Medical References

External Resources

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

Clinical Trials

Recent Publications

Latest News & Developments

Primary amoebic meningoencephalitis: discovery and understanding of a novel disease.

Pharmacological Interventions in Primary Amoebic Meningoencephalitis: Clinical Challenges and Strategic Solutions.