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A brain sarcoma that is composed of malignant pleomorphic or spindle neoplastic cells typically demonstrating myogenic and/or chondroid differentiation. Cytoplasmic eosinophilic globules and myxoid stroma formation are usually present. It is associated with mutations in the DICER1 gene.
Biomarker and diagnostic research for primary intracranial sarcoma, DICER1-mutant has been reported in the published literature.
No clinical trials have been registered for primary intracranial sarcoma, DICER1-mutant.
11 publications have been identified in PubMed for primary intracranial sarcoma, DICER1-mutant. Research spans Case Report / Case Series (64%), Review / Meta-Analysis (18%), and Other (9%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 7 | 64% |
Data assembled from 2 of 12 sources · Last updated Sep 18, 2026, 7:14 PM UTC
Research summaries
2 |
18% |
Other research | 1 | 9% |
Testing and diagnosis research | 1 | 9% |
Koleják R (2026). [PMID: 41236848](https://pubmed.ncbi.nlm.nih.gov/41236848/). *Int J Surg Pathol*. [Case Report / Case Series]
Kappa SS (2026). [PMID: 41431327](https://pubmed.ncbi.nlm.nih.gov/41431327/). *Pediatr Blood Cancer*. [Other]
Fujita S (2026). [PMID: 41929546](https://pubmed.ncbi.nlm.nih.gov/41929546/). *Int Cancer Conf J*. [Case Report / Case Series]
Duan ZJ (2025). [PMID: 40494768](https://pubmed.ncbi.nlm.nih.gov/40494768/). *Zhonghua Bing Li Xue Za Zhi*. [Case Report / Case Series]
Honma H (2025). [PMID: 39522081](https://pubmed.ncbi.nlm.nih.gov/39522081/). *Brain Tumor Pathol*. [Case Report / Case Series]
Soni N (2025). [PMID: 39349307](https://pubmed.ncbi.nlm.nih.gov/39349307/). *AJNR Am J Neuroradiol*. [Review / Meta-Analysis]
Karia K (2025). [PMID: 39763457](https://pubmed.ncbi.nlm.nih.gov/39763457/). *Int J Surg Pathol*. [Review / Meta-Analysis]
Lachance A (2024). [PMID: 38478067](https://pubmed.ncbi.nlm.nih.gov/38478067/). *Childs Nerv Syst*. [Case Report / Case Series]
Ou LQ (2024). [PMID: 39648006](https://pubmed.ncbi.nlm.nih.gov/39648006/). *Zhonghua Bing Li Xue Za Zhi*. [Case Report / Case Series]
Eldaya RW (2024). [PMID: 38637027](https://pubmed.ncbi.nlm.nih.gov/38637027/). *AJNR Am J Neuroradiol*. [Diagnostic / Biomarker]
AI-curated news mentioning primary intracranial sarcoma, DICER1-mutant
Updated Jun 2, 2026
A case report details a rare instance of primary intracranial Ewing-like sarcoma that led to rapid bilateral blindness. This finding contributes to the understanding of the disease's clinical presentation and potential implications for diagnosis.