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A rare biliary tract disease characterized by stone formation within the intrahepatic bile ducts without any known cause, leading to bile stasis and repeated cholangitic episodes.
Biomarker and diagnostic research for primary intrahepatic lithiasis has been reported in the published literature.
No clinical trials have been registered for primary intrahepatic lithiasis.
7 publications have been identified in PubMed for primary intrahepatic lithiasis. Research spans Clinical Trial Publication (57%), Diagnostic / Biomarker (29%), and Epidemiology / Natural History (14%).
Nunes TF (2026). [PMID: 41184458](https://pubmed.ncbi.nlm.nih.gov/41184458/). *Cardiovasc Intervent Radiol*. [Clinical Trial Publication]
Scaravaglio M (2026). [PMID: 40769470](https://pubmed.ncbi.nlm.nih.gov/40769470/). *Clin Gastroenterol Hepatol*. [Diagnostic / Biomarker]
De Rose AM (2025). [PMID: 40179530](https://pubmed.ncbi.nlm.nih.gov/40179530/). *Surgery*. [Clinical Trial Publication]
Vullierme MP (2025). [PMID: 40359291](https://pubmed.ncbi.nlm.nih.gov/40359291/). *Eur J Gastroenterol Hepatol*. [Diagnostic / Biomarker]
Ye YQ (2024). [PMID: 39091711](https://pubmed.ncbi.nlm.nih.gov/39091711/). *World J Gastroenterol*. [Clinical Trial Publication]
Data assembled from 3 of 12 sources · Last updated Sep 18, 2026, 8:51 AM UTC
European rare disease database
Genetic and Rare Diseases Info Center
Garcia FOB (2024). [PMID: 39699381](https://pubmed.ncbi.nlm.nih.gov/39699381/). *Arq Bras Cir Dig*. [Clinical Trial Publication]