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primary melanoma of the central nervous system - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

primary melanoma of the central nervous system

MONDO:0016747

Also known as:CNS melanomaCentral nervous system melanomacentral nervous system melanoma (disease)

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Overview

A melanoma that affects the central nervous system. It is characterized by pleomorphism, melanin pigmentation, a high mitotic rate, necrosis, and hemorrhage. It is a highly aggressive and radioresistant tumor. The prognosis is usually poor.

Clinical Trials1 registered

Diagnosis

Biomarker and diagnostic research for primary melanoma of the central nervous system has been reported in the published literature.

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

1 clinical trial registered. Interventions under study include procedural interventions and biologic therapy. Pipeline includes 1 PHASE1. Research is primarily sponsored by academic and government institutions.

85 publications have been identified in PubMed for primary melanoma of the central nervous system. Research spans Case Report / Case Series (35%), Review / Meta-Analysis (15%), and Clinical Trial Publication (13%).

Research Type	Count	% of Total
Patient case studies	30

Data assembled from 4 of 12 sources · Last updated Sep 20, 2026, 5:36 PM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:252050

GARD

Genetic and Rare Diseases Info Center

GARD:12016

Questions for Your Care Team

→Are any of the 1 active clinical trial a good fit for my situation?
→Are there specialists or centers of excellence for this condition in my area?
→Is there a patient registry I should consider joining?

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primary melanoma of the central nervous system

Overview

Diagnosis

Research Landscape

Medical References

External Resources

Orphanet

GARD

Subtypes

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

Recent Publications