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pulmonary non-tuberculous mycobacterial infection - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

pulmonary non-tuberculous mycobacterial infection

MONDO:0018469

Also known as:Nontuberculous Mycobacterial Lung Diseasenon-tuberculous mycobacterial lung disease

Find Clinical TrialsTrials

Overview

TreatmentsNo approved treatments · 1 in pipeline

Clinical Trials9 registered · 3 recruiting

Patient Orgs1 organizations · NTM Info & Research, Inc.

Diagnosis

Biomarker and diagnostic research for pulmonary non-tuberculous mycobacterial infection has been reported in the published literature.

Treatment

Compiled from FDA-approved drug records, orphan drug designations, and FDA Adverse Event Reporting System (FAERS) safety data. GeneReviews management guidance is included where available.

No approved treatments are currently available for pulmonary non-tuberculous mycobacterial infection. An additional 1 compound holds orphan drug designation.

Orphan Drug Designations

While no drugs are FDA-approved specifically for pulmonary non-tuberculous mycobacterial infection, some of the following designated compounds may be used off-label in clinical practice. Treatment decisions should be made in consultation with a specialist familiar with this condition.

The following drugs have received orphan drug designation from the FDA for pulmonary non-tuberculous mycobacterial infection. Orphan designation reflects regulatory interest and does not indicate approval for treatment.

Brand Name	Generic Name	Sponsor

Prognosis

Estimated prevalence: 1-9 in 100,000 (Uncommon).

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

9 clinical trials registered, 3 recruiting. Interventions under study include other interventions, biologic therapy, drug therapy, and medical devices. Pipeline includes 2 PHASE4. Research is primarily sponsored by academic and government institutions.

NCT ID	Title	Phase	Sponsor	Status
[NCT05192057](https://clinicaltrials.gov/study/NCT05192057)

Data assembled from 5 of 12 sources · Last updated Sep 20, 2026, 8:43 AM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Patient Support

Patient Advocacy Groups

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NTM Info & Research, Inc.Primary Focus

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Patient Advocacy Groups (PAGs) provide support, resources, and community for patients and caregivers.

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Medical References

External Resources

Orphanet

European rare disease database

Orphanet:411703

GARD

Genetic and Rare Diseases Info Center

GARD:12829

Questions for Your Care Team

→Are any of the 9 active clinical trials a good fit for my situation?
→What is the current development status of nitric oxide, and when might it become available?
→Are there specialists or centers of excellence for this condition in my area?
→How can I connect with NTM Info & Research, Inc. and other patient organizations for support?

← Back to All Diseases

Research Type	Count	% of Total
Disease patterns and progression	13	27%
Testing and diagnosis research	10	20%
Laboratory research	9	18%
Research summaries	6	12%
Patient case studies	5	10%
Clinical study results	3	6%
Other research	2	4%
New treatment approaches	1	2%

Kisho

pulmonary non-tuberculous mycobacterial infection

Overview

Diagnosis

Treatment

Orphan Drug Designations

Prognosis

Research Landscape

Patient Support

Patient Advocacy Groups

Medical References

External Resources

Orphanet

GARD

Questions for Your Care Team

Questions for Your Care Team

Clinical Trials

Recent Publications

Latest News & Developments

Mycobacterial periprosthetic joint infection of the hip and knee: current concepts in diagnosis and management.

Fallopian tube nontuberculous mycobacterial infection caused by Mycobacterium abscessus mimicking fallopian tube carcinoma: A case report.

Microscopic Polyangiitis After Pulmonary Nontuberculous Mycobacterial Disease: A Case Report and Literature Review.

pulmonary non-tuberculous mycobacterial infection

Overview

Diagnosis

Treatment

Orphan Drug Designations

Prognosis

Research Landscape

Patient Support

Patient Advocacy Groups

Medical References

External Resources

Orphanet

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

Clinical Trials

Recent Publications

Latest News & Developments

Mycobacterial periprosthetic joint infection of the hip and knee: current concepts in diagnosis and management.

Fallopian tube nontuberculous mycobacterial infection caused by Mycobacterium abscessus mimicking fallopian tube carcinoma: A case report.

Microscopic Polyangiitis After Pulmonary Nontuberculous Mycobacterial Disease: A Case Report and Literature Review.