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A palmoplantar keratosis characterized by keratoses with a "raindrop" pattern on the palmoplantar surface, skin lesions which may involve the whole of the palmoplantar surface, or may be more restricted in their distribution.
No clinical trials have been registered for punctate palmoplantar keratoderma.
7 publications have been identified in PubMed for punctate palmoplantar keratoderma. Research spans Case Report / Case Series (71%), Basic Science / Preclinical (14%), and Epidemiology / Natural History (14%).
Sarkar N (2026). [PMID: 41675017](https://pubmed.ncbi.nlm.nih.gov/41675017/). *JAAD case reports*. [Case Report / Case Series]
Zhang Z (2026). [PMID: 41925125](https://pubmed.ncbi.nlm.nih.gov/41925125/). *Journal of cutaneous medicine and surgery*. [Case Report / Case Series]
Ahmad DS (2025). [PMID: 41031278](https://pubmed.ncbi.nlm.nih.gov/41031278/). *Clinical case reports*. [Case Report / Case Series]
Gram SB (2025). [PMID: 39630431](https://pubmed.ncbi.nlm.nih.gov/39630431/). *JAMA dermatology*. [Epidemiology / Natural History]
Mastrangelo M (2025). [PMID: 40492104](https://pubmed.ncbi.nlm.nih.gov/40492104/). *JAAD case reports*. [Case Report / Case Series]
Data assembled from 3 of 12 sources · Last updated Sep 18, 2026, 7:13 PM UTC
European rare disease database
Genetic and Rare Diseases Info Center
Edwards TM (2024). [PMID: 39654849](https://pubmed.ncbi.nlm.nih.gov/39654849/). *JAAD case reports*. [Case Report / Case Series]
Gram SB (2024). [PMID: 38311882](https://pubmed.ncbi.nlm.nih.gov/38311882/). *Clinical genetics*. [Basic Science / Preclinical]