Kisho is an information platform, not a medical provider. Nothing on this site constitutes medical advice, diagnosis, or treatment recommendations. All content is aggregated from publicly available sources (including ClinicalTrials.gov, PubMed, FDA.gov, and Orphanet) and is provided for informational purposes only. Clinical trial eligibility, treatment decisions, and any health-related actions should always be discussed with a qualified healthcare professional. Kisho does not endorse any specific therapy, organization, or clinical trial. Terms of use · Privacy policy
A disease characterized by normocytic, normochromic anemia, low hematocrit, reticulocytopenia, and selective erythroid hypoplasia.
Biomarker and diagnostic research for pure red-cell aplasia has been reported in the published literature.
5 clinical trials registered, 2 recruiting. Interventions under study include drug therapy, procedural interventions, other interventions, and biologic therapy. Pipeline includes 4 PHASE2. Research is primarily sponsored by academic and government institutions.
NCT ID | Title | Phase | Sponsor | Status |
|---|---|---|---|---|
[NCT07031115](https://clinicaltrials.gov/study/NCT07031115) |
Data assembled from 3 of 12 sources · Last updated Sep 19, 2026, 9:39 PM UTC
Genetic and Rare Diseases Info Center
Linperlisib in the Treatment of aPRCA |
PHASE2 |
Peking Union Medical College Hospital |
NOT_YET_RECRUITING |
[NCT06412497](https://clinicaltrials.gov/study/NCT06412497) | MT2023-20: Hematopoietic Cell Transplant With Reduced Intensity Conditioning and Post-transplant Cyclophosphamide for Severe Aplastic Anemia and Other Forms of Acquired Bone Marrow Failure. | PHASE2 | Masonic Cancer Center, University of Minnesota | RECRUITING |
[NCT06065852](https://clinicaltrials.gov/study/NCT06065852) | National Registry of Rare Kidney Diseases | — | UK Kidney Association | RECRUITING |
[NCT05559827](https://clinicaltrials.gov/study/NCT05559827) | Efficacy of the antiCD38 Monoclonal Antibody Isatuximab in the Treatment of PCRA by Major ABO Mismatch After Allogeneic Hematopoietic Stem Cell Transplantation | PHASE2 | Assistance Publique - Hôpitaux de Paris | NOT_YET_RECRUITING |
[NCT03214354](https://clinicaltrials.gov/study/NCT03214354) | Nonmyeloablative Stem Cell Transplant in Children With Sickle Cell Disease and a Major ABO-Incompatible Matched Sibling Donor | PHASE2 | University of Calgary | UNKNOWN |
107 publications have been identified in PubMed for pure red-cell aplasia. Research spans Case Report / Case Series (46%), Review / Meta-Analysis (22%), and Basic Science / Preclinical (10%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 49 | 46% |
Research summaries | 24 | 22% |
Laboratory research | 11 | 10% |
Disease patterns and progression | 11 | 10% |
Other research | 5 | 5% |
Clinical study results | 5 | 5% |
Testing and diagnosis research | 1 | 1% |
New treatment approaches | 1 | 1% |
Kogler V (2026). [PMID: 40998264](https://pubmed.ncbi.nlm.nih.gov/40998264/). *Transplant Cell Ther*. [Epidemiology / Natural History]
Bisiou S (2026). [PMID: 41554971](https://pubmed.ncbi.nlm.nih.gov/41554971/). *Ann Hematol*. [Review / Meta-Analysis]
Serrano B (2026). [PMID: 42206211](https://pubmed.ncbi.nlm.nih.gov/42206211/). *Kidney Med*. [Case Report / Case Series]
Moreno Fonseca P (2026). [PMID: 42154736](https://pubmed.ncbi.nlm.nih.gov/42154736/). *Am J Case Rep*. [Case Report / Case Series]
Haque W (2026). [PMID: 40983285](https://pubmed.ncbi.nlm.nih.gov/40983285/). *J Thorac Oncol*. [Review / Meta-Analysis]
Noguchi Y (2026). [PMID: 41430035](https://pubmed.ncbi.nlm.nih.gov/41430035/). *Int J Hematol*. [Clinical Trial Publication]
Okamoto Y (2026). [PMID: 41421026](https://pubmed.ncbi.nlm.nih.gov/41421026/). *J Infect Chemother*. [Case Report / Case Series]
Zaw S (2026). [PMID: 41658747](https://pubmed.ncbi.nlm.nih.gov/41658747/). *Cureus*. [Case Report / Case Series]
Ansara Y (2026). [PMID: 41640448](https://pubmed.ncbi.nlm.nih.gov/41640448/). *Case Rep Med*. [Case Report / Case Series]
Mangla A (2026). [PMID: 31751023](https://pubmed.ncbi.nlm.nih.gov/31751023/). *Unknown Journal*. [Review / Meta-Analysis]
AI-curated news mentioning pure red-cell aplasia
Updated Sep 15, 2026
A recent study published in PubMed explores acquired pure red cell aplasia as a secondary condition linked to indolent mature T-cell lymphoid malignancy. This research contributes to the understanding of the disease's pathophysiology and potential treatment avenues.
A recent case report highlights the emergence of pure red cell aplasia following COVID-19 infection, contributing to the understanding of post-viral complications. This literature review may inform future research and clinical approaches to managing similar cases.
A recent study published in PubMed explores the use of Roxadustat for treating pure red cell aplasia associated with anti-EPO antibodies. This research could provide insights into alternative treatment options for patients suffering from this rare condition.