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A small blood vessel hemorrhage into the skin and/or mucous membranes. Newer lesions appear reddish in color. Older lesions are usually a darker purple color and eventually become a brownish-yellow color.
Biomarker and diagnostic research for purpura has been reported in the published literature.
53 clinical trials registered, 30 recruiting. Interventions under study include drug therapy, other interventions, procedural interventions, and biologic therapy. Pipeline includes 1 PHASE4, 5 PHASE3, 7 PHASE2. Research is sponsored by a mix of industry and academic institutions.
NCT ID | Title | Phase | Sponsor | Status |
|---|---|---|---|---|
[NCT05571774](https://clinicaltrials.gov/study/NCT05571774) |
Data assembled from 3 of 12 sources · Last updated Sep 19, 2026, 3:30 AM UTC
Construction of a Database for TTP |
— |
The First Affiliated Hospital of Soochow University |
RECRUITING |
[NCT06757257](https://clinicaltrials.gov/study/NCT06757257) | Special Drug Use-results Survey for Long-term Use (Fostamatinib) | — | Kissei Pharmaceutical Co., Ltd. | RECRUITING |
[NCT04890041](https://clinicaltrials.gov/study/NCT04890041) | TPO-RA in Primary Immune Thrombocytopenia (ITP) in Patients Older Than 14 Years | NA | Institute of Hematology & Blood Diseases Hospital, China | RECRUITING |
[NCT06722235](https://clinicaltrials.gov/study/NCT06722235) | A Study of Mezagitamab in Adults With Chronic Primary Immune Thrombocytopenia | PHASE3 | Takeda | RECRUITING |
[NCT07441525](https://clinicaltrials.gov/study/NCT07441525) | UCAR-T Targeting CD19/BCMA in Subjects With Autoantibody-Mediated Autoimmune Benign Hematological Diseases | EARLY_PHASE1 | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | RECRUITING |
319 publications have been identified in PubMed for purpura. Kisho has analyzed 174 by research type. Research spans Review / Meta-Analysis (44%), Case Report / Case Series (22%), and Epidemiology / Natural History (11%).
Research Type | Count | % of Total |
|---|---|---|
Research summaries | 76 | 44% |
Patient case studies | 38 | 22% |
Disease patterns and progression | 19 | 11% |
Clinical study results | 12 | 7% |
Laboratory research | 12 | 7% |
Testing and diagnosis research | 8 | 5% |
Other research | 7 | 4% |
New treatment approaches | 2 | 1% |
Roache-Robinson P (2026). [PMID: 30725937](https://pubmed.ncbi.nlm.nih.gov/30725937/). *Unknown Journal*. [Review / Meta-Analysis]
Mei H (2026). [PMID: 41237341](https://pubmed.ncbi.nlm.nih.gov/41237341/). *Blood*. [Basic Science / Preclinical]
Wang Y (2026). [PMID: 42004652](https://pubmed.ncbi.nlm.nih.gov/42004652/). *Kidney Med*. [Other]
Dolatshahi L (2026). [PMID: 41916552](https://pubmed.ncbi.nlm.nih.gov/41916552/). *Pediatr Rev*. [Review / Meta-Analysis]
Abdul Gafoor SM (2026). [PMID: 40795257](https://pubmed.ncbi.nlm.nih.gov/40795257/). *Clin Exp Dermatol*. [Review / Meta-Analysis]
Carter MA (2026). [PMID: 41692098](https://pubmed.ncbi.nlm.nih.gov/41692098/). *J Thromb Haemost*. [Review / Meta-Analysis]
Tang M (2026). [PMID: 41201304](https://pubmed.ncbi.nlm.nih.gov/41201304/). *Br J Haematol*. [Basic Science / Preclinical]
Kühne L (2026). [PMID: 41159657](https://pubmed.ncbi.nlm.nih.gov/41159657/). *Am J Hematol*. [Other]
Scully M (2026). [PMID: 41770788](https://pubmed.ncbi.nlm.nih.gov/41770788/). *Blood*. [Review / Meta-Analysis]
Hillier K (2026). [PMID: 41672375](https://pubmed.ncbi.nlm.nih.gov/41672375/). *J Thromb Haemost*. [Review / Meta-Analysis]