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An intermediate, locally aggressive and rarely metastasizing blood vessel neoplasm. It is characterized by the presence of hobnail endothelial cells and formation of arborizing vascular channels.
Estimated prevalence: <1 in 1,000,000 (VERY_RARE).
No clinical trials have been registered for retiform hemangioendothelioma.
7 publications have been identified in PubMed for retiform hemangioendothelioma. Research spans Case Report / Case Series (57%), Review / Meta-Analysis (29%), and Other (14%).
Hardy NJ (2026). [PMID: 41362870](https://pubmed.ncbi.nlm.nih.gov/41362870/). *JAAD Case Rep*. [Case Report / Case Series]
Song L (2025). [PMID: 39823973](https://pubmed.ncbi.nlm.nih.gov/39823973/). *Int J Surg Case Rep*. [Case Report / Case Series]
Bui T (2025). [PMID: 39562259](https://pubmed.ncbi.nlm.nih.gov/39562259/). *Semin Diagn Pathol*. [Review / Meta-Analysis]
Folpe AL (2024). [PMID: 38360216](https://pubmed.ncbi.nlm.nih.gov/38360216/). *Hum Pathol*. [Review / Meta-Analysis]
Xu B (2024). [PMID: 38757668](https://pubmed.ncbi.nlm.nih.gov/38757668/). *Ear Nose Throat J*. [Case Report / Case Series]
Ullah H (2024). [PMID: 39015637](https://pubmed.ncbi.nlm.nih.gov/39015637/). *Case Rep Oncol*. [Case Report / Case Series]
Data assembled from 3 of 12 sources · Last updated Sep 20, 2026, 3:03 PM UTC
European rare disease database
Genetic and Rare Diseases Info Center
Arcaira JA (2024). [PMID: 38780065](https://pubmed.ncbi.nlm.nih.gov/38780065/). *Int J Dermatol*. [Other]