A bilateral retinopathy characterized by neovascularization, scarring, retinal detachment, and eventually blindness. It may be mild or severe. It occurs in babies born prematurely. Causes include oxyg...
Comprehensive, easy-to-understand information about this condition
How we create this content →The documentation surrounding retinopathy of prematurity is limited largely due to its rarity and the challenges associated with studying conditions that affect a small population. As ROP primarily occurs in premature infants, the variability in clinical presentation and outcomes complicates systematic research. Additionally, the lack of identified genetic factors further contributes to the gaps in our understanding of this condition.
To navigate retinopathy of prematurity effectively, consider seeking a pediatric ophthalmologist with expertise in retinal disorders. They can provide specialized care and monitoring for your child. Additionally, you may want to explore participation in clinical trials to access cutting-edge treatments. For more information on genetic counseling and resources, you can visit the National Society of Genetic Counselors at https://www.nsgc.org. Engaging with a clinical trial may also provide insights into the latest research and treatment options.
There are several orphan drugs designated for the treatment of retinopathy of prematurity, including aflibercept, which is FDA-approved. Other drugs in development include various compounds such as Melatonin and Propranolol. Currently, there are 29 active clinical trials aimed at understanding and treating ROP. For more information on these trials, you can visit the ClinicalTrials.gov search page at https://clinicaltrials.gov/search?cond=retinopathy%20of%20prematurity.
Actionable guidance for navigating care for retinopathy of prematurity
To navigate retinopathy of prematurity effectively, consider seeking a pediatric ophthalmologist with expertise in retinal disorders. They can provide specialized care and monitoring for your child. Additionally, you may want to explore participation in clinical trials to access cutting-edge treatments. For more information on genetic counseling and resources, you can visit the National Society of Genetic Counselors at https://www.nsgc.org. Engaging with a clinical trial may also provide insights into the latest research and treatment options.
Consider asking your healthcare providers these condition-specific questions
Helpful links for rare disease information and support
The documentation surrounding retinopathy of prematurity is limited largely due to its rarity and the challenges associated with studying conditions that affect a small population. As ROP primarily occurs in premature infants, the variability in clinical presentation and outcomes complicates systematic research. Additionally, the lack of identified genetic factors further contributes to the gaps in our understanding of this condition.
To navigate retinopathy of prematurity effectively, consider seeking a pediatric ophthalmologist with expertise in retinal disorders. They can provide specialized care and monitoring for your child. Additionally, you may want to explore participation in clinical trials to access cutting-edge treatments. For more information on genetic counseling and resources, you can visit the National Society of Genetic Counselors at https://www.nsgc.org. Engaging with a clinical trial may also provide insights into the latest research and treatment options.
There are several orphan drugs designated for the treatment of retinopathy of prematurity, including aflibercept, which is FDA-approved. Other drugs in development include various compounds such as Melatonin and Propranolol. Currently, there are 29 active clinical trials aimed at understanding and treating ROP. For more information on these trials, you can visit the ClinicalTrials.gov search page at https://clinicaltrials.gov/search?cond=retinopathy%20of%20prematurity.
Actionable guidance for navigating care for retinopathy of prematurity
To navigate retinopathy of prematurity effectively, consider seeking a pediatric ophthalmologist with expertise in retinal disorders. They can provide specialized care and monitoring for your child. Additionally, you may want to explore participation in clinical trials to access cutting-edge treatments. For more information on genetic counseling and resources, you can visit the National Society of Genetic Counselors at https://www.nsgc.org. Engaging with a clinical trial may also provide insights into the latest research and treatment options.
Consider asking your healthcare providers these condition-specific questions
Helpful links for rare disease information and support
The documentation surrounding retinopathy of prematurity is limited largely due to its rarity and the challenges associated with studying conditions that affect a small population. As ROP primarily occurs in premature infants, the variability in clinical presentation and outcomes complicates systematic research. Additionally, the lack of identified genetic factors further contributes to the gaps in our understanding of this condition.
To navigate retinopathy of prematurity effectively, consider seeking a pediatric ophthalmologist with expertise in retinal disorders. They can provide specialized care and monitoring for your child. Additionally, you may want to explore participation in clinical trials to access cutting-edge treatments. For more information on genetic counseling and resources, you can visit the National Society of Genetic Counselors at https://www.nsgc.org. Engaging with a clinical trial may also provide insights into the latest research and treatment options.
There are several orphan drugs designated for the treatment of retinopathy of prematurity, including aflibercept, which is FDA-approved. Other drugs in development include various compounds such as Melatonin and Propranolol. Currently, there are 29 active clinical trials aimed at understanding and treating ROP. For more information on these trials, you can visit the ClinicalTrials.gov search page at https://clinicaltrials.gov/search?cond=retinopathy%20of%20prematurity.
Actionable guidance for navigating care for retinopathy of prematurity
To navigate retinopathy of prematurity effectively, consider seeking a pediatric ophthalmologist with expertise in retinal disorders. They can provide specialized care and monitoring for your child. Additionally, you may want to explore participation in clinical trials to access cutting-edge treatments. For more information on genetic counseling and resources, you can visit the National Society of Genetic Counselors at https://www.nsgc.org. Engaging with a clinical trial may also provide insights into the latest research and treatment options.
Consider asking your healthcare providers these condition-specific questions
Helpful links for rare disease information and support
Clinical profile data for this condition is not yet available. Phenotype information may still be loading below.
Research studies investigating treatments and therapies for this condition.
Active Trials
Total Trials
Data from ClinicalTrials.gov Jan 30, 2026
Consider asking your healthcare providers these condition-specific questions
European rare disease database
Genetic and Rare Diseases Info Center
AI-Generated Content: This summary was generated using AI. Content has been fact-checked. Always consult with qualified healthcare providers for medical guidance.
Organizations with approved therapies for this disease
No approved therapies yet
Research is ongoing — 11 companies have orphan drug designations for this disease
Kisho delivers this disease record via API, including phenotypes (HPO), genes, orphan drug designations, screening status, and PAG mapping, with version history and governance.