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A rhabdoid tumor that arises from the kidney. It occurs in children and it is associated with abnormalities of chromosome 22. It is characterized by the presence of cells with a large eccentric nucleus, prominent nucleolus, and abundant cytoplasm. The prognosis is poor.
Biomarker and diagnostic research for rhabdoid tumor of the kidney has been reported in the published literature.
6 clinical trials registered. Interventions under study include drug therapy, other interventions, procedural interventions, and biologic therapy. Pipeline includes 2 PHASE3, 2 PHASE2, 1 PHASE1. Research is primarily sponsored by academic and government institutions.
NCT ID | Title | Phase | Sponsor | Status |
|---|---|---|---|---|
[NCT04416568](https://clinicaltrials.gov/study/NCT04416568) |
Data assembled from 3 of 12 sources · Last updated Sep 20, 2026, 4:47 PM UTC
Study of Nivolumab and Ipilimumab in Children and Young Adults With INI1-Negative Cancers |
PHASE2 |
Dana-Farber Cancer Institute |
ACTIVE_NOT_RECRUITING |
[NCT00945009](https://clinicaltrials.gov/study/NCT00945009) | Combination Chemotherapy and Surgery in Treating Young Patients With Wilms Tumor | PHASE3 | Children's Oncology Group | UNKNOWN |
[NCT05407441](https://clinicaltrials.gov/study/NCT05407441) | Tazemetostat+Nivo/Ipi in INI1-Neg/SMARCA4-Def Tumors | PHASE1 | Susan Chi, MD | ACTIVE_NOT_RECRUITING |
[NCT00898365](https://clinicaltrials.gov/study/NCT00898365) | Study of Kidney Tumors in Younger Patients | — | Children's Oncology Group | UNKNOWN |
[NCT03793166](https://clinicaltrials.gov/study/NCT03793166) | Immunotherapy With Nivolumab and Ipilimumab Followed by Nivolumab or Nivolumab With Cabozantinib for Patients With Advanced Kidney Cancer, The PDIGREE Study | PHASE3 | National Cancer Institute (NCI) | ACTIVE_NOT_RECRUITING |
89 publications have been identified in PubMed for rhabdoid tumor of the kidney. Research spans Case Report / Case Series (28%), Review / Meta-Analysis (20%), and Basic Science / Preclinical (18%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 25 | 28% |
Research summaries | 18 | 20% |
Laboratory research | 16 | 18% |
Disease patterns and progression | 14 | 16% |
New treatment approaches | 6 | 7% |
Testing and diagnosis research | 5 | 6% |
Clinical study results | 5 | 6% |
Patil R (2026). [PMID: 42012842](https://pubmed.ncbi.nlm.nih.gov/42012842/). *Ann Afr Med*. [Case Report / Case Series]
Hughes K (2026). [PMID: 42073152](https://pubmed.ncbi.nlm.nih.gov/42073152/). *Children (Basel)*. [Epidemiology / Natural History]
Yao WQ (2026). [PMID: 41607752](https://pubmed.ncbi.nlm.nih.gov/41607752/). *World journal of gastrointestinal oncology*. [Case Report / Case Series]
Smith JP (2026). [PMID: 42063695](https://pubmed.ncbi.nlm.nih.gov/42063695/). *Front Oncol*. [Clinical Trial Publication]
Tsujio N (2026). [PMID: 42049324](https://pubmed.ncbi.nlm.nih.gov/42049324/). *Anticancer Res*. [Basic Science / Preclinical]
Montiel Equihua C (2026). [PMID: 41680284](https://pubmed.ncbi.nlm.nih.gov/41680284/). *Br J Cancer*. [Review / Meta-Analysis]
Yu Y (2026). [PMID: 41785935](https://pubmed.ncbi.nlm.nih.gov/41785935/). *Hum Pathol*. [Basic Science / Preclinical]
Uruga H (2026). [PMID: 42124357](https://pubmed.ncbi.nlm.nih.gov/42124357/). *Pathol Int*. [Case Report / Case Series]
Berry K (2026). [PMID: 42194920](https://pubmed.ncbi.nlm.nih.gov/42194920/). *J Clin Med*. [Basic Science / Preclinical]
Vidac A (2026). [PMID: 42195158](https://pubmed.ncbi.nlm.nih.gov/42195158/). *Medicina (Kaunas)*. [Epidemiology / Natural History]
AI-curated news mentioning rhabdoid tumor of the kidney
Updated Mar 26, 2026
A new report from the Pediatric Surgical Oncology Research Collaborative details outcomes and surgical management strategies for malignant rhabdoid tumor of the kidney. This research provides insights into treatment approaches for this rare pediatric cancer.
A recent analysis from the National Cancer Database investigates the effects of radiation therapy on malignant rhabdoid tumors of the kidney. This study provides insights that could influence treatment protocols for this rare pediatric cancer.