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Rieger's anomaly is a congenital ocular defect caused by anterior segment dysgenesis and is characterized by severe anterior chamber deformity with prominent strands and marked atrophy of the iris stroma, with hole or pseudo-hole formation and corectopia. The term covers the association of these iris and pupil anomalies with the features of AxenfeldBs anomaly.
No clinical trials have been registered for Rieger anomaly.
13 publications have been identified in PubMed for Rieger anomaly. Research spans Case Report / Case Series (54%), Review / Meta-Analysis (23%), and Basic Science / Preclinical (15%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 7 | 54% |
Research summaries | 3 |
Data assembled from 3 of 12 sources · Last updated Sep 18, 2026, 6:35 AM UTC
European rare disease database
Genetic and Rare Diseases Info Center
Common questions about Rieger anomaly
Laboratory research | 2 | 15% |
Disease patterns and progression | 1 | 8% |
Chaturvedi R (2026). [PMID: 41948357](https://pubmed.ncbi.nlm.nih.gov/41948357/). *JCEM Case Rep*. [Case Report / Case Series]
Tripathy K (2026). [PMID: 30860739](https://pubmed.ncbi.nlm.nih.gov/30860739/). *Unknown Journal*. [Review / Meta-Analysis]
Fischer MC (2026). [PMID: 41139957](https://pubmed.ncbi.nlm.nih.gov/41139957/). *HGG advances*. [Case Report / Case Series]
Saha BC (2026). [PMID: 41936534](https://pubmed.ncbi.nlm.nih.gov/41936534/). *Eur J Ophthalmol*. [Review / Meta-Analysis]
Schuknecht A (2025). [PMID: 39870091](https://pubmed.ncbi.nlm.nih.gov/39870091/). *Klinische Monatsblatter fur Augenheilkunde*. [Case Report / Case Series]
Tajima K (2025). [PMID: 40420722](https://pubmed.ncbi.nlm.nih.gov/40420722/). *Journal of diabetes investigation*. [Case Report / Case Series]
Ohkubo Y (2025). [PMID: 40741157](https://pubmed.ncbi.nlm.nih.gov/40741157/). *Radiology case reports*. [Case Report / Case Series]
Yang Y (2025). [PMID: 41459015](https://pubmed.ncbi.nlm.nih.gov/41459015/). *Therapeutic advances in endocrinology and metabolism*. [Case Report / Case Series]
Syed Iqbaluddin J (2024). [PMID: 39044864](https://pubmed.ncbi.nlm.nih.gov/39044864/). *Cureus*. [Case Report / Case Series]
Untaroiu A (2024). [PMID: 38587439](https://pubmed.ncbi.nlm.nih.gov/38587439/). *Investigative ophthalmology & visual science*. [Basic Science / Preclinical]