Rombo syndrome is a rare condition that shows several skin and hair changes. It is characterized by features such as vermiculate atrophoderma (a pattern of skin atrophy), milia (small white bumps), hypotrichosis (sparse hair), and trichoepitheliomas (small, benign hair follicle tumors). People with this condition may also experience peripheral vasodilation with cyanosis, which means there is an abnormal widening of small blood vessels that can lead to a bluish discoloration of the skin, as well as basal cell carcinomas, a type of skin cancer. This summary is based on the available description of the disease characteristics.

The signs of Rombo syndrome include a unique pattern of skin atrophy known as vermiculate atrophoderma, the development of milia, and less hair than usual (hypotrichosis). Additionally, people with this condition may develop trichoepitheliomas, experience widened blood vessels that can cause a blue tint in the skin (peripheral vasodilation with cyanosis), and may have basal cell carcinomas.

Information about causes is currently limited for this condition.