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A sex cord-gonadal stromal tumor consists of leydig cells; sertoli cells; and fibroblasts in varying proportions and degree of differentiation. Most such tumors produce androgens in the Leydig cells, formerly known as androblastoma or arrhenoblastoma. Androblastomas occur in the testis or the ovary causing precocious masculinization in the males, and defeminization, or virilization (virilism) in the females. In some cases, the Sertoli cells produce estrogens.
Biomarker and diagnostic research for Sertoli-Leydig cell tumor has been reported in the published literature.
3 clinical trials registered, 2 recruiting. Interventions under study include other interventions and drug therapy. Pipeline includes 1 PHASE2. Research is primarily sponsored by academic and government institutions.
97 publications have been identified in PubMed for Sertoli-Leydig cell tumor. Research spans Case Report / Case Series (54%), Basic Science / Preclinical (16%), and Review / Meta-Analysis (11%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 52 |
Data assembled from 3 of 12 sources · Last updated Sep 19, 2026, 1:10 PM UTC
Common questions about Sertoli-Leydig cell tumor
Laboratory research | 16 | 16% |
Research summaries | 11 | 11% |
Testing and diagnosis research | 8 | 8% |
Other research | 4 | 4% |
Disease patterns and progression | 4 | 4% |
Clinical study results | 2 | 2% |
Wang J (2026). [PMID: 42204407](https://pubmed.ncbi.nlm.nih.gov/42204407/). *J Clin Ultrasound*. [Review / Meta-Analysis]
Trecourt A (2026). [PMID: 41545266](https://pubmed.ncbi.nlm.nih.gov/41545266/). *Ann Pathol*. [Basic Science / Preclinical]
Hu WQ (2026). [PMID: 42221431](https://pubmed.ncbi.nlm.nih.gov/42221431/). *Int J Womens Health*. [Case Report / Case Series]
Biegańska O (2026). [PMID: 42049361](https://pubmed.ncbi.nlm.nih.gov/42049361/). *Anticancer Res*. [Case Report / Case Series]
Zhu Z (2026). [PMID: 41928129](https://pubmed.ncbi.nlm.nih.gov/41928129/). *BMC Pregnancy Childbirth*. [Case Report / Case Series]
Kim HS (2026). [PMID: 41243833](https://pubmed.ncbi.nlm.nih.gov/41243833/). *Adv Anat Pathol*. [Review / Meta-Analysis]
Němejcová K (2026). [PMID: 41839237](https://pubmed.ncbi.nlm.nih.gov/41839237/). *Mod Pathol*. [Diagnostic / Biomarker]
Nalluri BT (2026). [PMID: 41486225](https://pubmed.ncbi.nlm.nih.gov/41486225/). *Indian J Pediatr*. [Case Report / Case Series]
Yazıcı MC (2026). [PMID: 41778968](https://pubmed.ncbi.nlm.nih.gov/41778968/). *Fetal Pediatr Pathol*. [Case Report / Case Series]
Trecourt A (2026). [PMID: 41255082](https://pubmed.ncbi.nlm.nih.gov/41255082/). *Am J Surg Pathol*. [Basic Science / Preclinical]