Kisho is an information platform, not a medical provider. Nothing on this site constitutes medical advice, diagnosis, or treatment recommendations. All content is aggregated from publicly available sources (including ClinicalTrials.gov, PubMed, FDA.gov, and Orphanet) and is provided for informational purposes only. Clinical trial eligibility, treatment decisions, and any health-related actions should always be discussed with a qualified healthcare professional. Kisho does not endorse any specific therapy, organization, or clinical trial. Terms of use · Privacy policy
Spinocerebellar ataxia type 32 (SCA32) is a subtype of autosomal dominant cerebellar ataxia type 1 (ADCA type 1) characterized by ataxia, cognitive impairment and azoospermia in males.
Features include common findings: Difficulty with thinking and memory (cognitive impairment), Shrinkage of the cerebellum (cerebellar atrophy), Testicular atrophy, and Azoospermia and others. 8 total HPO annotations.
Organ System | Phenotype Count | Example Features |
|---|---|---|
Brain and nerves | 3 | Difficulty with thinking and memory (cognitive impairment), Ataxia, Progressive cerebellar ataxia |
Biomarker and diagnostic research for spinocerebellar ataxia type 32 has been reported in the published literature.
Phenotype severity distribution: 6 common features.
Estimated prevalence: <1 in 1,000,000 (VERY_RARE).
1 clinical trial registered, 1 recruiting. Interventions under study include other interventions. Research is primarily sponsored by academic and government institutions.
47 publications have been identified in PubMed for spinocerebellar ataxia type 32. Kisho has analyzed 29 by research type. Research spans Case Report / Case Series (24%), Diagnostic / Biomarker (21%), and Epidemiology / Natural History (21%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 7 |
Data assembled from 6 of 12 sources · Last updated Sep 20, 2026, 4:33 PM UTC
Online Mendelian Inheritance in Man
European rare disease database
Genetic and Rare Diseases Info Center
Muscles |
2 |
Shrinkage of the cerebellum (cerebellar atrophy), Testicular atrophy |
Hormones | 2 | Infertility, Male infertility |
Testing and diagnosis research | 6 | 21% |
Disease patterns and progression | 6 | 21% |
Clinical study results | 4 | 14% |
Laboratory research | 4 | 14% |
Research summaries | 1 | 3% |
New treatment approaches | 1 | 3% |
Zamora-Fung R (2026). [PMID: 41831049](https://pubmed.ncbi.nlm.nih.gov/41831049/). *Cerebellum*. [Epidemiology / Natural History]
Petit E (2026). [PMID: 41150672](https://pubmed.ncbi.nlm.nih.gov/41150672/). *Brain*. [Diagnostic / Biomarker]
Chiu C (2026). [PMID: 41756352](https://pubmed.ncbi.nlm.nih.gov/41756352/). *Exp Ther Med*. [Diagnostic / Biomarker]
Lan SC (2025). [PMID: 41082794](https://pubmed.ncbi.nlm.nih.gov/41082794/). *Parkinsonism Relat Disord*. [Epidemiology / Natural History]
Chen X (2025). [PMID: 40532663](https://pubmed.ncbi.nlm.nih.gov/40532663/). *Cell Rep Med*. [Clinical Trial Publication]
Villaruz LC (2025). [PMID: 41160399](https://pubmed.ncbi.nlm.nih.gov/41160399/). *Cancer*. [Clinical Trial Publication]
Sarma GR (2025). [PMID: 39934002](https://pubmed.ncbi.nlm.nih.gov/39934002/). *Ann Indian Acad Neurol*. [Case Report / Case Series]
Rybarikova M (2025). [PMID: 40721863](https://pubmed.ncbi.nlm.nih.gov/40721863/). *Gene Ther*. [Gene Therapy / Novel Therapeutics]
Theuriet J (2025). [PMID: 40579842](https://pubmed.ncbi.nlm.nih.gov/40579842/). *Eur J Neurol*. [Epidemiology / Natural History]
Pelosi L (2025). [PMID: 40554381](https://pubmed.ncbi.nlm.nih.gov/40554381/). *Clin Neurophysiol*. [Diagnostic / Biomarker]
AI-curated news mentioning spinocerebellar ataxia type 32
Updated Aug 18, 2026
A recent study published in PubMed details the clinical features of four unrelated Japanese patients diagnosed with autosomal recessive spinocerebellar ataxia type 32. This research contributes to the understanding of the disease's presentation and may inform future studies.