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A progressive neurodegenerative disorder caused by a disruption in the connection between the striatum and the substantia nigra. It is a type of multiple system atrophy (MSA). Signs and symptoms include rigidity, instability, impaired speech, and slow movements.
No clinical trials have been registered for striatonigral degeneration.
10 publications have been identified in PubMed for striatonigral degeneration. Research spans Review / Meta-Analysis (33%), Case Report / Case Series (22%), and Other (11%).
Gebre RK (2026). [PMID: 41912595](https://pubmed.ncbi.nlm.nih.gov/41912595/). *Sci Rep*. [Epidemiology / Natural History]
Xiao S (2026). [PMID: 41738058](https://pubmed.ncbi.nlm.nih.gov/41738058/). *Neuropsychiatr Dis Treat*. [Review / Meta-Analysis]
Lindsay R (2026). [PMID: 40888261](https://pubmed.ncbi.nlm.nih.gov/40888261/). *Mov Disord Clin Pract*. [Case Report / Case Series]
Garg S (2026). [PMID: 41232996](https://pubmed.ncbi.nlm.nih.gov/41232996/). *Neurol Clin*. [Review / Meta-Analysis]
Cuinat S (2025). [PMID: 40443206](https://pubmed.ncbi.nlm.nih.gov/40443206/). *Mov Disord Clin Pract*. [Other]
Calakos N (2025). [PMID: 39467044](https://pubmed.ncbi.nlm.nih.gov/39467044/). *Mov Disord*. [Review / Meta-Analysis]
Data assembled from 2 of 12 sources · Last updated Sep 19, 2026, 6:44 AM UTC
Jeon E (2024). [PMID: 39578419](https://pubmed.ncbi.nlm.nih.gov/39578419/). *Cell Death Dis*. [Basic Science / Preclinical]
Tang D (2024). [PMID: 39716170](https://pubmed.ncbi.nlm.nih.gov/39716170/). *BMC Med Genomics*. [Case Report / Case Series]
Kodam V (2024). [PMID: 39428949](https://pubmed.ncbi.nlm.nih.gov/39428949/). *Ann Indian Acad Neurol*. [Clinical Trial Publication]