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Features include always present findings: Neuronal loss in central nervous system. 26 total HPO annotations.
Organ System | Phenotype Count | Example Features |
|---|---|---|
Brain and nerves | 15 | Slowness of movement (bradykinesia), Muscle stiffness (rigidity), Gait imbalance |
Biomarker and diagnostic research for supranuclear palsy, progressive, 2 has been reported in the published literature.
Phenotype severity distribution: 1 always present feature.
No clinical trials have been registered for supranuclear palsy, progressive, 2.
239 publications have been identified in PubMed for supranuclear palsy, progressive, 2. Research spans Basic Science / Preclinical (27%), Diagnostic / Biomarker (22%), and Epidemiology / Natural History (19%).
Research Type | Count | % of Total |
|---|---|---|
Laboratory research | 64 | 27% |
Data assembled from 4 of 12 sources · Last updated Sep 19, 2026, 1:00 PM UTC
Online Mendelian Inheritance in Man
Genetic and Rare Diseases Info Center
2 |
Diplopia, Blurred vision |
Digestive system | 1 | Difficulty swallowing (dysphagia) |
Bones and joints | 1 | Postural tremor |
Muscles | 1 | Falls |
Testing and diagnosis research
53 |
22% |
Disease patterns and progression | 45 | 19% |
Research summaries | 29 | 12% |
Clinical study results | 24 | 10% |
Patient case studies | 17 | 7% |
New treatment approaches | 4 | 2% |
Other research | 3 | 1% |
Vöglein J (2026). [PMID: 41721140](https://pubmed.ncbi.nlm.nih.gov/41721140/). *J Neurol*. [Case Report / Case Series]
Hebron LP (2026). [PMID: 42104994](https://pubmed.ncbi.nlm.nih.gov/42104994/). *J Neurol*. [Clinical Trial Publication]
Kwon EH (2026). [PMID: 41745712](https://pubmed.ncbi.nlm.nih.gov/41745712/). *Neurol Int*. [Epidemiology / Natural History]
Garg RK (2026). [PMID: 41493643](https://pubmed.ncbi.nlm.nih.gov/41493643/). *Neurol Sci*. [Review / Meta-Analysis]
Li E (2026). [PMID: 41501928](https://pubmed.ncbi.nlm.nih.gov/41501928/). *Trials*. [Clinical Trial Publication]
Nagel G (2026). [PMID: 41730149](https://pubmed.ncbi.nlm.nih.gov/41730149/). *Neurology*. [Epidemiology / Natural History]
Bruno MK (2026). [PMID: 40842097](https://pubmed.ncbi.nlm.nih.gov/40842097/). *Mov Disord Clin Pract*. [Review / Meta-Analysis]
Liang M (2026). [PMID: 41474764](https://pubmed.ncbi.nlm.nih.gov/41474764/). *Clin Nucl Med*. [Diagnostic / Biomarker]
Saibaba J (2026). [PMID: 42084970](https://pubmed.ncbi.nlm.nih.gov/42084970/). *Ann Indian Acad Neurol*. [Other]
Arca VM (2026). [PMID: 42135922](https://pubmed.ncbi.nlm.nih.gov/42135922/). *Ann Neurol*. [Diagnostic / Biomarker]