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A neurological disorder characterized by rapid, jerky, irregular, and involuntary movements (chorea), especially of the face and limbs. Additional symptoms may include muscle weakness, slurred speech, headaches, and seizures.
Estimated prevalence: Unknown (Unknown prevalence).
1 clinical trial registered, 1 recruiting. Interventions under study include drug therapy. Pipeline includes 1 PHASE3. Research is primarily sponsored by academic and government institutions.
21 publications have been identified in PubMed for Sydenham chorea. Research spans Case Report / Case Series (47%), Basic Science / Preclinical (21%), and Review / Meta-Analysis (16%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 9 | 47% |
Data assembled from 4 of 12 sources · Last updated Sep 19, 2026, 1:53 PM UTC
European rare disease database
Genetic and Rare Diseases Info Center
Common questions about Sydenham chorea
Laboratory research |
4 |
21% |
Research summaries | 3 | 16% |
Disease patterns and progression | 2 | 11% |
Other research | 1 | 5% |
Xu Z (2026). [PMID: 41497421](https://pubmed.ncbi.nlm.nih.gov/41497421/). *Cureus*. [Case Report / Case Series]
Baizabal-Carvallo JF (2026). [PMID: 41633741](https://pubmed.ncbi.nlm.nih.gov/41633741/). *Handbook of clinical neurology*. [Epidemiology / Natural History]
Zamani MH (2026). [PMID: 41185949](https://pubmed.ncbi.nlm.nih.gov/41185949/). *Physical & occupational therapy in pediatrics*. [Case Report / Case Series]
Teixeira AL (2026). [PMID: 41989060](https://pubmed.ncbi.nlm.nih.gov/41989060/). *Expert Rev Clin Immunol*. [Review / Meta-Analysis]
Jaronik JM (2025). [PMID: 39927111](https://pubmed.ncbi.nlm.nih.gov/39927111/). *Tremor and other hyperkinetic movements (New York, N.Y.)*. [Basic Science / Preclinical]
Ozbudak P (2025). [PMID: 39636055](https://pubmed.ncbi.nlm.nih.gov/39636055/). *Journal of child neurology*. [Case Report / Case Series]
Gangwal R (2025). [PMID: 41503084](https://pubmed.ncbi.nlm.nih.gov/41503084/). *Indian J Psychiatry*. [Other]
Han VX (2025). [PMID: 40859454](https://pubmed.ncbi.nlm.nih.gov/40859454/). *Annals of clinical and translational neurology*. [Case Report / Case Series]
Thomas T (2025). [PMID: 41265690](https://pubmed.ncbi.nlm.nih.gov/41265690/). *Pediatrics*. [Review / Meta-Analysis]
Mohod SV (2025). [PMID: 41185661](https://pubmed.ncbi.nlm.nih.gov/41185661/). *Cureus*. [Case Report / Case Series]