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Symmetrical thalamic calcifications are clinically distinguished by a low Apgar score, spasticity or marked hypotonia, weak or absent cry, poor feeding, and facial diplegia or weakness.
Biomarker and diagnostic research for symmetrical thalamic calcifications has been reported in the published literature.
Estimated prevalence: <1 in 1,000,000 (VERY_RARE).
No clinical trials have been registered for symmetrical thalamic calcifications.
2 publications have been identified in PubMed for symmetrical thalamic calcifications. Research spans Diagnostic / Biomarker (50%) and Case Report / Case Series (50%).
Alrashidi FS (2026). [PMID: 41625059](https://pubmed.ncbi.nlm.nih.gov/41625059/). *Cureus*. [Case Report / Case Series]
Albazron FM (2025). [PMID: 40782678](https://pubmed.ncbi.nlm.nih.gov/40782678/). *Pediatric neurology*. [Diagnostic / Biomarker]
Data assembled from 3 of 12 sources · Last updated Nov 4, 2026, 4:45 AM UTC
European rare disease database
Genetic and Rare Diseases Info Center