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teratoma - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

teratoma

MONDO:0002601

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Overview

A non-seminomatous germ cell tumor characterized by the presence of various tissues which correspond to the different germinal layers (endoderm, mesoderm, and ectoderm). It occurs in the testis, ovary, and extragonadal sites including central nervous system, mediastinum, lung, and stomach. According to the level of differentiation of the tissues which comprise the tumor, teratomas are classified as mature or immature. Mature teratomas are composed of well differentiated, adult-type tissues. Immature teratomas are composed of immature, fetal-type tissues. Testicular teratomas in children follow a benign clinical course. Mature ovarian teratomas without a fetal-type component have an excellent outcome. The prognosis of immature ovarian teratomas is related to the grade and stage of the tumor.

Clinical Trials8 registered · 3 recruiting

Diagnosis

Biomarker and diagnostic research for teratoma has been reported in the published literature.

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

8 clinical trials registered, 3 recruiting. Interventions under study include procedural interventions, other interventions, drug therapy, and biologic therapy. Pipeline includes 2 PHASE3, 2 PHASE2, 1 NA. Research is primarily sponsored by academic and government institutions.

NCT ID	Title	Phase	Sponsor	Status
[NCT06421805](https://clinicaltrials.gov/study/NCT06421805)

Data assembled from 3 of 12 sources · Last updated Sep 18, 2026, 4:55 PM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

Questions for Your Care Team

→Are any of the 8 active clinical trials a good fit for my situation?
→Are there specialists or centers of excellence for this condition in my area?
→Is there a patient registry I should consider joining?

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Research Type	Count	% of Total
Patient case studies	47	44%
Research summaries	27	25%
Disease patterns and progression	11	10%
Laboratory research	9	8%
Testing and diagnosis research	5	5%
Clinical study results	4	4%
New treatment approaches	3	3%
Other research	1	1%

Kisho

teratoma

Overview

Diagnosis

Research Landscape

Medical References

Questions for Your Care Team

Questions for Your Care Team

Recent Publications

Latest News & Developments

Metachronous Pineal Germinoma 11 Years After Total Resection of a Mature Teratoma.

Growing teratoma syndrome of the ovary: a case series.

teratoma

Overview

Diagnosis

Research Landscape

Medical References

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

Recent Publications

Latest News & Developments

Metachronous Pineal Germinoma 11 Years After Total Resection of a Mature Teratoma.

Growing teratoma syndrome of the ovary: a case series.