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Features include always present findings: Menorrhagia, Abnormal bleeding tendency (abnormal bleeding), Low platelet count (thrombocytopenia), and Decreased mean platelet volume; and common findings: Bruising susceptibility, Petechiae, and Spontaneous, recurrent epistaxis.
Organ System | Phenotype Count | Example Features |
|---|---|---|
Blood and immune system | 3 | Abnormal bleeding tendency (abnormal bleeding), Low platelet count (thrombocytopenia), Decreased mean platelet volume |
PTPRJ function has not been fully characterized.
Thrombocytopenia 10 has limited evidence linking it to mutations in the PTPRJ gene on chromosome 11.
Genetic testing for PTPRJ is available. Testing is considered research-grade for diagnosis.
Phenotype severity distribution: 4 always present features, 3 common features.
No clinical trials have been registered for thrombocytopenia 10.
21 publications have been identified in PubMed for thrombocytopenia 10. Research spans Clinical Trial Publication (52%), Epidemiology / Natural History (19%), and Case Report / Case Series (14%).
Research Type | Count | % of Total |
|---|---|---|
Clinical study results | 11 | 52% |
Data assembled from 6 of 12 sources · Last updated Sep 19, 2026, 9:39 PM UTC
Online Mendelian Inheritance in Man
Age of onset: at birth.
4 |
19% |
Patient case studies | 3 | 14% |
Research summaries | 2 | 10% |
Laboratory research | 1 | 5% |
Hulej G (2026). [PMID: 42082379](https://pubmed.ncbi.nlm.nih.gov/42082379/). *Lupus Sci Med*. [Epidemiology / Natural History]
Zhou T (2026). [PMID: 42022538](https://pubmed.ncbi.nlm.nih.gov/42022538/). *MedComm (2020)*. [Clinical Trial Publication]
Zhang J (2026). [PMID: 41930344](https://pubmed.ncbi.nlm.nih.gov/41930344/). *MedComm*. [Clinical Trial Publication]
Kühne L (2026). [PMID: 41671477](https://pubmed.ncbi.nlm.nih.gov/41671477/). *Blood*. [Clinical Trial Publication]
Colombo N (2026). [PMID: 41950571](https://pubmed.ncbi.nlm.nih.gov/41950571/). *European journal of cancer (Oxford, England : 1990)*. [Clinical Trial Publication]
Perimbeti S (2025). [PMID: 41315064](https://pubmed.ncbi.nlm.nih.gov/41315064/). *Cancer chemotherapy and pharmacology*. [Clinical Trial Publication]
Belhaj R (2025). [PMID: 39842709](https://pubmed.ncbi.nlm.nih.gov/39842709/). *Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine*. [Epidemiology / Natural History]
Vedpathak S (2025). [PMID: 39710119](https://pubmed.ncbi.nlm.nih.gov/39710119/). *Virus research*. [Basic Science / Preclinical]
He S (2025). [PMID: 40934436](https://pubmed.ncbi.nlm.nih.gov/40934436/). *Immunotherapy*. [Clinical Trial Publication]
Bisson GB (2025). [PMID: 40474359](https://pubmed.ncbi.nlm.nih.gov/40474359/). *Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry*. [Case Report / Case Series]