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tooth ankylosis - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

tooth ankylosis

MONDO:0008007

Also known as:ankylosis (disease) of calcareous toothankylosis of teethankylosis of tooth

Overview

Dental ankylosis is a rare disorder characterized by the fusion of the tooth to the bone, preventing both eruption and orthodontic movement.

GeneticsAutosomal dominant

Patient Orgs1 organizations · US TOO International, Inc.

Clinical Presentation

Built from Human Phenotype Ontology (HPO) phenotype annotations and GeneReviews clinical descriptions. Features represent findings documented across known cases — not an exhaustive list of possible symptoms.

Features include: Abnormality of the dentition, Clinodactyly of the 5th finger, and Mandibular prognathia.

Organ System	Phenotype Count	Example Features
Arms and legs	1	Clinodactyly of the 5th finger
Head and neck

Diagnosis

Biomarker and diagnostic research for tooth ankylosis has been reported in the published literature.

Prognosis

Estimated prevalence: Unknown (Unknown prevalence).

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

No clinical trials have been registered for tooth ankylosis.

40 publications have been identified in PubMed for tooth ankylosis. Research spans Case Report / Case Series (38%), Epidemiology / Natural History (20%), and Basic Science / Preclinical (13%).

Research Type	Count	% of Total
Patient case studies	15	38%

Data assembled from 5 of 12 sources · Last updated Sep 19, 2026, 7:47 AM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Patient Support

Patient Advocacy Groups

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US TOO International, Inc.Primary Focus

USWebsite ↗

Patient Advocacy Groups (PAGs) provide support, resources, and community for patients and caregivers.

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Medical References

External Resources

OMIM

Online Mendelian Inheritance in Man

OMIM:157950

Orphanet

European rare disease database

Orphanet:1077

GARD

Genetic and Rare Diseases Info Center

GARD:701

Questions for Your Care Team

→Are there specialists or centers of excellence for this condition in my area?
→How can I connect with US TOO International, Inc. and other patient organizations for support?

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Kisho

tooth ankylosis

Overview

Clinical Presentation

Diagnosis

Prognosis

Research Landscape

Patient Support

Patient Advocacy Groups

Medical References

External Resources

OMIM

Orphanet

GARD

Questions for Your Care Team

Questions for Your Care Team

Explore clinical features

Recent Publications

tooth ankylosis

Overview

Clinical Presentation

Diagnosis

Prognosis

Research Landscape

Patient Support

Patient Advocacy Groups

Medical References

External Resources

OMIM

Orphanet

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

Explore clinical features

Recent Publications