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undifferentiated (embryonal) sarcoma (UES) - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

undifferentiated (embryonal) sarcoma

MONDO:0005102

Also known as:UESembryonal sarcomaembryonal sarcoma (undifferentiated sarcoma)

Find Clinical TrialsTrials

Overview

An aggressive malignant mesenchymal neoplasm that arises from the liver and usually occurs in older children. It is composed of immature spindle, stellate, polymorphous, and giant cells.

Clinical Trials8 registered · 4 recruiting

Diagnosis

Biomarker and diagnostic research for undifferentiated (embryonal) sarcoma has been reported in the published literature.

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

8 clinical trials registered, 4 recruiting. Interventions under study include drug therapy, gene therapy, other interventions, and procedural interventions. Pipeline includes 2 PHASE2, 5 PHASE1. Research is primarily sponsored by academic and government institutions.

NCT ID	Title	Phase	Sponsor	Status
[NCT07148050](https://clinicaltrials.gov/study/NCT07148050)

Data assembled from 3 of 12 sources · Last updated Sep 19, 2026, 8:28 PM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

Questions for Your Care Team

→Are any of the 8 active clinical trials a good fit for my situation?
→Are there specialists or centers of excellence for this condition in my area?
→Is there a patient registry I should consider joining?

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Research Type	Count	% of Total
Patient case studies	31	55%
Research summaries	8	14%
Other research	4	7%
Laboratory research	4	7%
Clinical study results	3	5%
Disease patterns and progression	3	5%
Testing and diagnosis research	2	4%
New treatment approaches	1	2%

Kisho

undifferentiated (embryonal) sarcoma

Overview

Diagnosis

Research Landscape

Medical References

Questions for Your Care Team

Questions for Your Care Team

Recent Publications

Latest News & Developments

Clinicopathologic Study of 39 Mismatch Repair-deficient Sarcomas Demonstrates Recurrent Histologic Patterns and Supports Universal Screening of Pleomorphic Rhabdomyosarcoma, Uterine Leiomyosarcoma, and Undifferentiated and Unclassified Sarcomas.

undifferentiated (embryonal) sarcoma

Overview

Diagnosis

Research Landscape

Medical References

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

Recent Publications

Latest News & Developments

Clinicopathologic Study of 39 Mismatch Repair-deficient Sarcomas Demonstrates Recurrent Histologic Patterns and Supports Universal Screening of Pleomorphic Rhabdomyosarcoma, Uterine Leiomyosarcoma, and Undifferentiated and Unclassified Sarcomas.