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A rare form of amyloidosis characterized by accumulation and extensive visceral deposition of anamyloidogenic variant of beta 2 microglobulin leading to progressive gastrointestinal dysfunction, Sjögren syndrome and autonomic neuropathy.
Biomarker and diagnostic research for variant ABeta2M amyloidosis has been reported in the published literature.
Estimated prevalence: <1 in 1,000,000 (VERY_RARE).
No clinical trials have been registered for variant ABeta2M amyloidosis.
68 publications have been identified in PubMed for variant ABeta2M amyloidosis. Research spans Review / Meta-Analysis (24%), Epidemiology / Natural History (24%), and Case Report / Case Series (19%).
Research Type | Count | % of Total |
|---|---|---|
Research summaries | 16 | 24% |
Data assembled from 3 of 12 sources · Last updated Sep 19, 2026, 3:00 PM UTC
European rare disease database
Genetic and Rare Diseases Info Center
16 |
24% |
Patient case studies | 13 | 19% |
Testing and diagnosis research | 9 | 13% |
Laboratory research | 8 | 12% |
Clinical study results | 4 | 6% |
Other research | 1 | 1% |
New treatment approaches | 1 | 1% |
Hou W (2026). [PMID: 40115281](https://pubmed.ncbi.nlm.nih.gov/40115281/). *Ann Neurosci*. [Review / Meta-Analysis]
Di Certo MG (2026). [PMID: 41735206](https://pubmed.ncbi.nlm.nih.gov/41735206/). *Curr Gene Ther*. [Basic Science / Preclinical]
Yang X (2026). [PMID: 41736303](https://pubmed.ncbi.nlm.nih.gov/41736303/). *Alzheimers Dement*. [Basic Science / Preclinical]
Cappelli F (2026). [PMID: 41955077](https://pubmed.ncbi.nlm.nih.gov/41955077/). *Eur Heart J*. [Diagnostic / Biomarker]
Costa PIMCA (2026). [PMID: 41871624](https://pubmed.ncbi.nlm.nih.gov/41871624/). *Arq Neuropsiquiatr*. [Review / Meta-Analysis]
Bevilacqua JA (2026). [PMID: 42024697](https://pubmed.ncbi.nlm.nih.gov/42024697/). *Rev Med Chil*. [Review / Meta-Analysis]
Ahmed S (2026). [PMID: 41884769](https://pubmed.ncbi.nlm.nih.gov/41884769/). *Kidney Med*. [Case Report / Case Series]
Millat G (2026). [PMID: 42154990](https://pubmed.ncbi.nlm.nih.gov/42154990/). *Clin Chem Lab Med*. [Diagnostic / Biomarker]
Xiang S (2026). [PMID: 42232968](https://pubmed.ncbi.nlm.nih.gov/42232968/). *Front Med (Lausanne)*. [Case Report / Case Series]
Milam EC (2026). [PMID: 41700576](https://pubmed.ncbi.nlm.nih.gov/41700576/). *Am J Dermatopathol*. [Review / Meta-Analysis]