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vegetative pyoderma gangrenosum - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

vegetative pyoderma gangrenosum

MONDO:0035238

Also known as:Granulomatous pyoderma gangrenosum

Overview

A rare subtype of pyoderma gangrenosum disease characterized by a solitary, erythematous, ulcerated plaque, which lacks the violaceous border typically present in classic pyoderma gangrenosum, usually affecting individuals who are otherwise healthy. Histologically, the lesion presents a central layer containing neutrophilic inflammation, surrounded by a palisade of histiocytes, which are rimmed by a lymphocytic infiltrate. In comparison with the other variants of pyoderma gangrenosum, this subtype usually shows a good response to less aggressive treatments and underlying systemic disorders are less frequently associated. It is considered the most benign and uncommon clinical variant of pyoderma gangrenosum.

ResearchLimited published research (7 articles)

Prognosis

Estimated prevalence: Unknown (Unknown prevalence).

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

No clinical trials have been registered for vegetative pyoderma gangrenosum.

7 publications have been identified in PubMed for vegetative pyoderma gangrenosum. Research spans Case Report / Case Series (100%).

Recent Publications

Downey K (2026). [PMID: 42183091](https://pubmed.ncbi.nlm.nih.gov/42183091/). *JAAD Case Rep*. [Case Report / Case Series]
Tiwari D (2026). [PMID: 42084979](https://pubmed.ncbi.nlm.nih.gov/42084979/). *Indian Dermatol Online J*. [Case Report / Case Series]
Jadhav A (2025). [PMID: 40069562](https://pubmed.ncbi.nlm.nih.gov/40069562/). *Ann Afr Med*. [Case Report / Case Series]
Hoang M (2025). [PMID: 39787338](https://pubmed.ncbi.nlm.nih.gov/39787338/). *Am J Dermatopathol*. [Case Report / Case Series]
Shackle R (2025). [PMID: 40904167](https://pubmed.ncbi.nlm.nih.gov/40904167/). *Australas J Dermatol*. [Case Report / Case Series]
Becker SL (2025). [PMID: 39520260](https://pubmed.ncbi.nlm.nih.gov/39520260/). *Australas J Dermatol*. [Case Report / Case Series]

Data assembled from 3 of 12 sources · Last updated Sep 20, 2026, 5:49 AM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:538872

GARD

Genetic and Rare Diseases Info Center

GARD:22223

Questions for Your Care Team

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vegetative pyoderma gangrenosum

Overview

Prognosis

Research Landscape

Recent Publications

Medical References

External Resources

Orphanet

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team