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viral hemorrhagic fever - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

viral hemorrhagic fever

MONDO:0018087

Also known as:haemorrhagic feverhemorrhagic feverhemorrhagic fevers

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Overview

A viral infectious disease caused by RNA viruses in the Arenaviridae, Bunyaviridae, Filoviridae, or Flaviviridae family, and characterized by a severe multisystem syndrome, with damage to the vascular system and hemorrhaging.

TreatmentsNo approved treatments · 1 in pipeline

Clinical Trials18 registered · 7 recruiting

Diagnosis

Biomarker and diagnostic research for viral hemorrhagic fever has been reported in the published literature.

Treatment

Compiled from FDA-approved drug records, orphan drug designations, and FDA Adverse Event Reporting System (FAERS) safety data. GeneReviews management guidance is included where available.

No approved treatments are currently available for viral hemorrhagic fever. An additional 1 compound holds orphan drug designation.

Orphan Drug Designations

While no drugs are FDA-approved specifically for viral hemorrhagic fever, some of the following designated compounds may be used off-label in clinical practice. Treatment decisions should be made in consultation with a specialist familiar with this condition.

The following drugs have received orphan drug designation from the FDA for viral hemorrhagic fever. Orphan designation reflects regulatory interest and does not indicate approval for treatment.

Brand Name	Generic Name	Sponsor

Prognosis

Estimated prevalence: Unknown (Unknown prevalence).

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

18 clinical trials registered, 7 recruiting. Interventions under study include other interventions, drug therapy, biologic therapy, and medical devices. Pipeline includes 1 PHASE3, 3 PHASE2, 2 PHASE1. Research is sponsored by a mix of industry and academic institutions.

NCT ID	Title	Phase	Sponsor	Status
[NCT06624787](https://clinicaltrials.gov/study/NCT06624787)

Data assembled from 5 of 12 sources · Last updated Oct 3, 2026, 8:41 AM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:341

GARD

Genetic and Rare Diseases Info Center

GARD:5494

Questions for Your Care Team

→Are any of the 18 active clinical trials a good fit for my situation?
→What is the current development status of recombinant nematode anticoagulant protein c2 (rNAPc2), and when might it become available?
→Are there specialists or centers of excellence for this condition in my area?
→Is there a patient registry I should consider joining?

← Back to All Diseases

Research Type	Count	% of Total
Disease patterns and progression	42	26%
Research summaries	39	24%
Laboratory research	34	21%
Testing and diagnosis research	12	7%
New treatment approaches	12	7%
Other research	9	5%
Patient case studies	9	5%
Clinical study results	7	4%

Kisho

viral hemorrhagic fever

Overview

Diagnosis

Treatment

Orphan Drug Designations

Prognosis

Research Landscape

Medical References

External Resources

Orphanet

GARD

Questions for Your Care Team

Questions for Your Care Team

Clinical Trials

Recent Publications

Latest News & Developments

Unique Program Improves Rapid Detection of Deadly Outbreaks in Uganda - Press Release

viral hemorrhagic fever

Overview

Diagnosis

Treatment

Orphan Drug Designations

Prognosis

Research Landscape

Medical References

External Resources

Orphanet

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

Clinical Trials

Recent Publications

Latest News & Developments

Unique Program Improves Rapid Detection of Deadly Outbreaks in Uganda - Press Release