X-linked hereditary sensory and autonomic neuropathy with hearing loss

X-linked hereditary sensory and autonomic neuropathy with hearing loss is a rare condition that affects the nerves which help in sensing touch, pain, and temperature, and also impacts hearing. This syndrome is characterized by an axonal sensory and autonomic neuropathy along with hearing loss. In people with this condition, the nerves may not send signals properly, which can lead to difficulties in feeling sensations and issues with hearing. The condition is linked to changes in a gene called AIFM1. Being X-linked means that the condition is related to a gene on the X chromosome, which can affect the way the disorder is passed through families. Information about additional clinical features and variations in severity is currently limited for this condition.

People with this condition may experience problems with their sensory nerves such as reduced ability to feel pain or temperature, along with hearing loss. The hearing loss can affect the ability to follow conversations and may require further evaluation by specialists.

The cause of this condition is linked to mutations in the AIFM1 gene. It is inherited in an X-linked manner, meaning that the gene mutation is located on the X chromosome. This inheritance pattern influences how the condition appears in different family members.

Information about treatment is currently limited for this condition.

Information about prognosis is currently limited for this condition.

Information about research is currently limited for this condition.