X-linked intellectual disability, Seemanova type is a rare condition that affects brain development and overall growth. People with this condition can have a smaller head size (microcephaly), slower growth, and intellectual difficulties. The condition has been observed in four boys in one family and is passed down in an X-linked manner. In addition to the growth and intellectual challenges, a distinct facial appearance and eye problems have been noted. The eye issues include small eyes or parts of the eyes (microphthalmia and microcornea) and cataracts. This summary is based on the information provided in the trusted sources.

Common signs and symptoms include a smaller head size (microcephaly), intellectual difficulties, slower physical growth, and underdeveloped genitalia (hypogenitalism). Some people with this condition also show distinct facial features and eye problems, such as small eyes (microphthalmia), small parts of the eye (microcornea), and cataracts.

This disease is inherited through the X chromosome. It has been observed among boys in one family, indicating an X-linked pattern of transmission. The exact genetic changes responsible for this condition were not detailed in the source.