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Plain-language summaries of 10,888 rare conditions, drawn from MONDO, GeneReviews, ClinVar, FDA, NIH, ClinicalTrials.gov, PubMed, and 5 other public sources. Free, sourced, never gated.
Kisho provides public health information only — not medical advice. Always consult your healthcare provider.
12
authoritative sources — clinical, regulatory, scientific
10,888
rare conditions, continuously monitored
Daily
updates from MONDO, HPO, ClinicalTrials.gov, FDA, Orphanet…
Showing 8,761-8,780 of 10,888 diseases
MONDO:0004775
Lens-induced iridocyclitis is an ocular inflammatory condition that involves an immune response triggered by alterations in the lens, leading to infla...
MONDO:0007892
Lenz-Majewski hyperostotic dwarfism is an extremely rare condition characterized by dwarfism, a distinctive facial appearance, cutis laxa, and progres...
MONDO:0100082
LEOPARD syndrome 1 is a rare condition that falls under the group of disorders sometimes called Noonan syndrome with multiple lentigines. The conditio...
MONDO:0012691
LEOPARD syndrome 2 is a rare condition that falls under the group of Noonan syndromes with multiple lentigines. A key aspect of this condition is that...
MONDO:0013380
LEOPARD syndrome 3 is a rare genetic condition that falls under the group of Noonan syndromes with multiple lentigines. It is caused by a mutation in...
MONDO:0005127
Lepromatous leprosy is a chronic communicable infection caused by Mycobacterium leprae that primarily affects the skin and peripheral nerves. The cond...
MONDO:0005124
Leprosy is a chronic infectious disease that primarily affects the skin and peripheral nervous system. Several recognized subtypes have been described...
MONDO:0003761
Leptomeningeal melanoma is a malignant tumor that arises from melanocytes within the leptomeninges, the thin layers covering the brain and spinal cord...
MONDO:0004330
MONDO:0017084
Leptomyelolipoma is a rare neural tube closure defect in which the conus medullaris is abnormally low and tethered by a lumbosacral lipomatous mass. T...
MONDO:0005825
Leptospirosis is a contagious bacterial infection caused by spirochetes of the genus Leptospira, most commonly affecting individuals following exposur...
MONDO:0007894
Leri pleonosteosis is a condition marked by unique changes in the fingers and toes. People with this condition often have broadening and deformity of...
MONDO:0007481
Leri-Weill dyschondrosteosis (LWD) is a skeletal dysplasia, a condition that affects the development of bones. People with this condition often have a...
MONDO:0010642
Information about overview is currently limited for this condition.
MONDO:0010298
Lesch-Nyhan syndrome is a severe hereditary disorder of purine metabolism caused by pathogenic variants in the HPRT1 gene. The resulting enzyme defici...
MONDO:0001543
Lesion of sciatic nerve is a peripheral nerve lesion involving the large nerve that runs from the lower back down the leg. Recognized subtypes, such a...
MONDO:0030897
Lessel-Kreienkamp syndrome, also known as LESKRES, is a rare condition. It has been linked to changes in the AGO2 gene. Detailed explanations about wh...
MONDO:0012323
Lethal acantholytic epidermolysis bullosa is a severe skin condition classified as a subtype of epidermolysis bullosa simplex. It is characterized by...
MONDO:0017818
MONDO:0012750
Built from MONDO, HPO, ClinicalTrials.gov, FDA, Orphanet, and 7 more public sources. Updated daily.