The multi-drug partnership with Orbis Medicines—which Novo has backed since the biotech's seed rounds—is focused on cardiometabolic targets, but the technology at the center of the deal could deliver oral weight loss candidates. Obesity rival Eli Lilly has also helped fund Orbis.

Original title: “Novo notches up to $1.4B pact with Orbis to develop oral macrocycle cardiometabolic drugs”

Learn what manufacturing challenges lie ahead, how to equip your team to protect your program from avoidable manufacturing and regulatory setbacks and forge partnerships that can withstand the next five years of industry turbulence.

Original title: “Webinar: Manufacturing in Turbulent Times”

While increases in the interest rate from the Federal Reserve are usually bad for biotech, the sector at this moment is poised to withstand the blow, according to analysts, though earlier stage companies may be left in the lurch.

Original title: “Fed rate hike won’t hold biotech down despite climbing capital costs”

Big Pharma needs more—not fewer—bold bets on rare and difficult diseases after Novartis’ efforts to invest in muscular dystrophy and ALS hit major roadblocks this month.

Original title: “After Novartis’ devastating M&A losses, long live the executive willing to try”

Novartis stands alongside Big Pharma peers that have similarly invested in technologies to penetrate the blood-brain barrier, including GSK, Roche and Eli Lilly.

Original title: “Novartis drops $125M for Sironax’s tech to cross blood-brain barrier”

The partners will focus R&D efforts on immunological and inflammatory conditions using Dualitas’ DualScreen Bispecific Discovery Engine platform.

Original title: “Roche bets up to $1B to advance next-gen bispecifics with Dualitas”

As biopharma job openings rose this year, opportunities were greatest in Massachusetts and California and in the science/R&D and clinical disciplines, according to BioSpace data. Several other locations and functions have also been going strong.

Original title: “Biopharma hiring hotspots: States, disciplines where demand is highest”

From engineering to science/R&D, these top seven biopharma disciplines each have hundreds, and in one case over 1,000, positions posted on BioSpace.

Original title: “Trending: Top biopharma disciplines with jobs live now”