Investors had been pessimistic about the probability of success for the personalized cancer vaccine intismeran autogene, so the Phase 3 win was a welcome surprise.

Original title: “Merck’s Moderna-partnered vaccine success clears view of post-Keytruda future”

First guidance for a licensed hyperhidrosis treatment

Original title: “NICE backs Axhidrox for severe underarm sweating”

The U.S. Food and Drug Administration today authorized the Aletta, the first standalone robotic device that can draw blood from a patient’s arm without hands-on operator intervention.

Original title: “FDA Authorizes First-Of-Its-Kind Robotic Blood Draw Device”

Melanoma was slower to recur in patients receiving Merck and Moderna's mRNA vaccine with Keytruda, supporting use of the combination in adjuvant treatment. The partners plan to take the data to the FDA.

Original title: “Moderna stock nearly doubles as Merck-partnered mRNA cancer vaccine meets Phase 3 goal”

At an interim data check, investigators of a key trial found the individualized mRNA treatment kept disease from returning and stopped its spread, sparking a surge in Moderna shares.

Original title: “Moderna and Merck cancer vaccine returns ‘landmark’ result in melanoma”

Saffron trial delivers positive results

Original title: “Orpathys plus Tagrisso shows survival benefit in lung cancer”

Touting an “exceptional” gastrointestinal safety profile for its oral obesity drug candidate in a study of healthy volunteers, Enveda plans to test the asset in people stopping GLP-1 treatment.

Original title: “Enveda’s exercise-simulating obesity tablet clears early clinical test”

The FDA’s August approval of Takeda’s Orzeyful for treating the full set of narcolepsy symptoms initiated a new era in the sleep market.

Original title: “Takeda leads wave of orexin drugs with potential to upend narcolepsy market”

A combination of AstraZeneca’s Tagrisso and Hutchmed’s Orpathys extended survival for some lung cancer patients. Elsewhere, MapLight floated the idea of partnering on its autism drug.

Original title: “AstraZeneca scores in lung cancer; Sandoz inks a China deal”