This document contains proposed rules that would amend the regulations regarding excepted benefits under the Employee Retirement Income Security Act of 1974, the Internal Revenue Code, and the Public Health Service Act to establish certain fertility benefits as a new category of limited excepted benefits. Excepted benefits are generally exempt from the market requirements that were added to those laws by the Health Insurance Portability and Accountability Act, the Patient Protection and Affordab

Original title: “Excepted Fertility Benefits”

The Center for Drug Evaluation and Research (CDER) of the Food and Drug Administration (FDA or Agency) is announcing a request for information regarding a regulatory science initiative. The aims of the initiative are to advance biomarker validation through the compilation of data from multiple sources and through a specific pilot project focused on aggregating data for biomarkers of drug-induced kidney injury. The purpose of this notice is to inform the public of the aims of this initiative, to

Original title: “Biomarker Incubator: Urinary Kidney Safety Biomarkers; Request for Information”

The Food and Drug Administration (FDA or we) is requesting information on the current uses and safety data for butylated hydroxytoluene (BHT) in human food and as a food contact substance. We are requesting this information as part of our systematic process for conducting post-market assessments of chemicals in food. We are conducting a post-market assessment of the safety of BHT in food, considering the latest state of the science. We intend to use the information received and any other availab

Original title: “Butylated Hydroxytoluene (BHT); Request for Information”

The Food and Drug Administration (FDA or the Agency) is announcing the availability for public comment of modified risk tobacco product applications (MRTPAs) for renewal of existing MRTP orders for two cigarette products submitted by 22nd Century Group Inc.

Original title: “Modified Risk Tobacco Product Application: Renewal Applications for VLN® King and VLN® Menthol King, Cigarette Products Submitted by 22nd Century Group Inc.”

The Food and Drug Administration (FDA or we) is requesting information on the current uses and safety data of azodicarbonamide (ADA) in human food and as a food contact substance. We are requesting this information as part of our systematic process for conducting post- market assessments of chemicals in food. We are conducting a post- market assessment of the safety of ADA in food, considering the latest state of the science. We intend to use the information received and any other available, rel

Original title: “Azodicarbonamide (ADA); Request for Information”

This meeting notice announces the first public meeting of the Healthcare Advisory Committee (HAC or Committee). The purpose of the Committee is to advise the Secretary of HHS and the CMS Administrator on programs and policies that can improve the United States (U.S.) healthcare system consistent with the Executive Order Establishing the President's Make American Healthy Again Commission. This virtual meeting is open to the public.

Original title: “Healthcare Advisory Committee (HAC); Announcement of the HAC Meeting-May 18, 2026”

The Children's Bureau (CB), Administration for Children and Families (ACF) is requesting a 3-year extension of the collection of information under the Child and Family Services Plan (CFSP), the Annual Progress and Services Report (APSR), and the Annual Budget Expenses Request and Estimated Expenditures (CFS-101) collection (Office of Management and Budget #: 0970-0426, expiration July 31, 2026). There are minor changes to the CFS-101 form and changes to the way the information is collected in na

Original title: “Proposed Information Collection Activity; Child and Family Services Plan, Annual Progress and Services Report, and Annual Budget Expenses Request and Estimated Expenditures (Child and Family Services-101)”

FDA continues to implement its bold food agenda, with two decisive actions focused on food chemical safety.

Original title: “FDA Finalizes Food Chemical Safety Post-Market Assessment Program, Launches Reassessment of BHT, ADA”

The FDA is looking to retool drugs with sufficient evidence to support their use in other indications, particularly those with unmet need.

Original title: “FDA turns to old drugs to address new diseases, persistent medical needs”

EMA welcomes the provisional agreement reached by the European Parliament and the Council of the European Union on the proposed Critical Medicines Act (CMA), which represents an…, “At a time of increasing global disruptions, resilient and secure supply chains for critical medicines are essential to protect public health across the EU. Today’s…, In recent years, EU Member States have faced serious medicine shortages and global challenges such as the COVID-19 pandemic and geopolitical t

Original title: “EMA welcomes political agreement on Critical Medicines Act”

In this notice of proposed rulemaking (NPRM), the Administration for Children and Families (ACF) proposes to remove requirements from the Head Start Program Performance Standards (Performance Standards) to restore local flexibility to Head Start programs and improve access to quality services. Specifically, this NPRM proposes to remove requirements related to wages and benefits that the Administration believes are not in line with the plain language of the Head Start Act and are costly and overl

Original title: “Restoring Flexibility To Support Head Start Program Access”

The Food and Drug Administration (FDA) is classifying the device to detect and identify microorganism nucleic acids and resistance markers from patients with suspected orthopedic infection into class II (special controls). The special controls that apply to the device type are identified in this order and will be part of the codified language for classification of the device to detect and identify microorganism nucleic acids and resistance markers from patients with suspected orthopedic infectio

Original title: “Medical Devices; Immunology and Microbiology Devices; Classification of the Device To Detect and Identify Microorganism Nucleic Acids and Resistance Markers From Patients With Suspected Orthopedic Infection”

The Food and Drug Administration (FDA, the Agency, or we) is opening a public docket to solicit input and comments on FDA's efforts with respect to drug repurposing to address unmet medical needs. FDA is requesting information on potential priority disease areas and potential candidates for drug repurposing, with a focus on FDA-approved drugs for which there appears to be no commercial interest in adding a new use through a supplement to a new drug application (supplemental application). Informa

Original title: “Drug Repurposing for Unmet Medical Needs; Request for Information”

The Centers for Disease Control and Prevention (CDC), as part of its continuing effort to reduce public burden and maximize the utility of government information, invites the public and other federal agencies to comment on a continuing information collection, as required by the Paperwork Reduction Act of 1995. This notice invites comment on a proposed information collection project titled National Healthcare Safety Network (NHSN) Respiratory Data. The NHSN Respiratory Data collection provides si

Original title: “Proposed Data Collection Submitted for Public Comment and Recommendations”

The Food and Drug Administration (FDA, the Agency, or we) is announcing the availability of the Agency's annual compilation of notices of updates to the Agency's Susceptibility Test Interpretive Criteria web page. The Agency established the Susceptibility Test Interpretive Criteria web page on December 13, 2017, and since establishment has provided updates to both the format of the web pages and the susceptibility test interpretive criteria identified and recognized by FDA on the web pages. FDA

Original title: “21st Century Cures Act: Annual Compilation of Notices of Updates From the Susceptibility Test Interpretive Criteria web page”

This final rule amends the Child Care and Development Fund (CCDF) regulations to reduce costs and burden for States and Territories administering the CCDF program. It rescinds the requirements to limit family co-payments to 7 percent of family income, to provide some direct services through grants or contracts, to pay providers prospectively, and to pay providers based on enrollment. A plain language summary of this final rule is posted at https:// www.regulations.gov/document/ACF-2026-0001-0002

Original title: “Restoring Flexibility in the Child Care and Development Fund (CCDF)”

The Food and Drug Administration (FDA, Agency, or we) is announcing the availability of a final guidance for industry entitled "Enforcement Priorities for Certain New Tobacco Products Marketed Without Premarket Authorization." This guidance document describes certain enforcement policies with regard to the marketing of certain electronic nicotine delivery systems and oral nicotine pouch products that do not have premarket authorization.

Original title: “Enforcement Priorities for Certain New Tobacco Products Marketed Without Premarket Authorization; Guidance for Industry; Availability”

The Centers for Disease Control and Prevention (CDC), as part of its continuing effort to reduce public burden and maximize the utility of government information, invites the general public and other Federal agencies to comment on a continuing information collection, as required by the Paperwork Reduction Act of 1995. This notice invites comment on a proposed information collection project titled Information Collections to Advance State, Tribal, Local and Territorial (STLT) Governmental Agency S

Original title: “Proposed Data Collection Submitted for Public Comment and Recommendations”

The Centers for Disease Control and Prevention (CDC), as part of its continuing effort to reduce public burden and maximize the utility of government information, invites the general public and other federal agencies the opportunity to comment on a continuing information collection, as required by the Paperwork Reduction Act of 1995. This notice invites comment on a proposed information collection project titled National Healthcare Safety Network (NHSN). NHSN is the nation's most widely used hea

Original title: “Proposed Data Collection Submitted for Public Comment and Recommendations”