Explore Diseases Find Orgs Patient Assistance News Insights About

Kisho

Kisho is an information platform, not a medical provider. Nothing on this site constitutes medical advice, diagnosis, or treatment recommendations. All content is aggregated from publicly available sources (including ClinicalTrials.gov, PubMed, FDA.gov, and Orphanet) and is provided for informational purposes only. Clinical trial eligibility, treatment decisions, and any health-related actions should always be discussed with a qualified healthcare professional. Kisho does not endorse any specific therapy, organization, or clinical trial. Terms of use · Privacy policy

Open rare disease resources — free, sourced, never gated.

Resources

Rare Disease Directory
Patient Organization Directory
Patient Assistance Programs
Rare Disease News
Clinical Trials
Research Publications

Legal

Privacy Policy
Terms of Service
Accessibility
About & Methodology
Contact

What's new in your rare disease | Kisho

Not rare diseases news,
news about your rare disease.

Every story we pull is tagged to the disease it’s about — so you can filter to your condition and read only what matters.

News sourcesFDA·NIH·CDC·EMA·PubMed·Federal Register·NORD·EURORDIS·Global Genes·The Mighty·BioPharma Dive·BioSpace

Newsroom9,552 Trends

Daily Briefings

20 earlier

Filter & sort

Source

Sort by

Earlier

20 stories

Research

Maxillary sinusitis due to Burkholderia cepacia mimicking fungal sinusitis.

PubMed Rare Disease·12 days ago·Read at source →

Research

SLC20A2 Intragenic Structural Variants as a Cause of Primary Brain Calcification.

PubMed Rare Disease·12 days ago·Read at source →

chronic beryllium disease pulmonary sarcoidosisResearch

A national multicentre case-control study reveals distinct clinical presentations and prognoses for chronic beryllium disease compared to pulmonary sarcoidosis. This research enhances understanding of these conditions, potentially guiding future treatment approaches.

distinct clinical presentation and prognosis of chronic beryllium disease versus pulmonary sarcoidosis a national multicentre case control study

PubMed Rare Disease·12 days ago·Read at source →

Original title: “Distinct clinical presentation and prognosis of chronic beryllium disease versus pulmonary sarcoidosis: a national multicentre case-control study.”

Research

A recent study identifies rare Malton genotypes of the alpha-1 antitrypsin gene in a multicenter cohort from Southeastern Türkiye. This research enhances understanding of genetic variations associated with alpha-1 antitrypsin deficiency.

alpha 1 antitrypsin gene variants in southeastern t rkiye with identification of rare malton genotypes in a multicenter real world cohort

PubMed Rare Disease·12 days ago·Read at source →

Original title: “Alpha-1 Antitrypsin Gene Variants in Southeastern Türkiye with Identification of Rare Malton Genotypes in a Multicenter Real-world Cohort.”

Research

A new study highlights the association between pulmonary infiltrates and chronic elevation of blood circulating monocytes. This research could provide insights into underlying mechanisms of respiratory diseases linked to immune system dysregulation.

pulmonary infiltrates associated with chronic elevation of blood circulating monocytes

PubMed Rare Disease·12 days ago·Read at source →

Original title: “[Pulmonary infiltrates associated with chronic elevation of blood circulating monocytes].”

Research

A case report details an L5 corpectomy performed on a 12-year-old patient due to Rosai-Dorfman disease. This surgical intervention highlights the complexities of managing this rare condition in pediatric patients.

l5 corpectomy in a 12 year old owing to rosai dorfman disease a case report

PubMed Rare Disease·12 days ago·Read at source →

Original title: “L5 Corpectomy in a 12-Year-Old Owing to Rosai-Dorfman Disease: A Case Report.”

Research

A recent study identifies a correlation between immunoglobulin M levels and the risk of overwhelming post-splenectomy infection in patients with asplenia. This research could inform monitoring strategies for this vulnerable patient population.

link between immunoglobulin m levels and overwhelming post splenectomy infection risk in a national asplenia cohort

PubMed Rare Disease·12 days ago·Read at source →

Original title: “A Link Between Immunoglobulin M Levels and Overwhelming Post-Splenectomy Infection Risk in a National Asplenia Cohort.”

systemic sclerosis limited systemic sclerosis+1 moreResearch

Recent studies highlight emerging drugs in phase 2/3 and selected phase 1/2 trials for systemic sclerosis treatment. These developments may offer new therapeutic options for patients suffering from this challenging condition.

emerging drugs in phase 2 3 and selected phase 1 2 cellular therapy trials a glimpse into the future of systemic sclerosis treatment

PubMed Rare Disease·12 days ago·Read at source →

Original title: “Emerging drugs in phase 2/3 and selected phase 1/2 cellular-therapy trials: a glimpse into the future of systemic sclerosis treatment.”

Research

A recent study explores how preparation design and connector geometry affect the mechanical properties of additively manufactured periodontal splints. This research could inform future advancements in dental applications and materials.

preparation design and connector geometry influence the mechanical behavior of additively manufactured periodontal splints

PubMed Rare Disease·12 days ago·Read at source →

Original title: “Preparation design and connector geometry influence the mechanical behavior of additively manufactured periodontal splints.”

familial long QT syndrome congenital bowing of long bonesResearch

A recent study highlights the challenges in diagnosing congenital long QT syndrome type 2, with patients experiencing seizure-like episodes for over a decade before receiving accurate diagnoses. This research underscores the need for increased awareness and better diagnostic protocols for this rare condition.

congenital long qt syndrome type 2 delayed diagnosis after a decade of seizure like episodes

PubMed Rare Disease·12 days ago·Read at source →

Original title: “Congenital Long QT Syndrome Type 2: Delayed Diagnosis After a Decade of Seizure-Like Episodes.”

sickle cell disease sickle cell-hemoglobin d disease syndrome+1 moreResearch

A recent claims data analysis highlights trends in the epidemiology, healthcare utilization, and disease burden of sickle cell disease in Germany from 2015 to 2024. This study provides valuable insights into the management and impact of the disease in the German healthcare system.

sickle cell disease in germany trends in epidemiology healthcare utilization and disease burden from 2015 to 2024 a claims data analysis

PubMed Rare Disease·12 days ago·Read at source →

Original title: “Sickle cell disease in Germany - trends in epidemiology, healthcare utilization and disease burden from 2015 to 2024: a claims data analysis.”

Research

A new study highlights the mechanistic diversity in mitochondrial skeletal disorders, emphasizing that these conditions, while grouped, exhibit significant variability in their underlying mechanisms. This research could inform future therapeutic strategies and patient management.

grouped but not unified mechanistic diversity in mitochondrial skeletal disorders

PubMed Rare Disease·12 days ago·Read at source →

Original title: “Grouped but not unified: mechanistic diversity in mitochondrial skeletal disorders.”

multiple sclerosisResearch

A recent study highlights the genetic factors influencing multiple sclerosis, linking specific genes to disease susceptibility, severity, and progression. This research could inform future therapeutic strategies and patient management.

clinical relevance of multiple sclerosis genetics from susceptibility to disease severity and progression

PubMed Rare Disease·12 days ago·Read at source →

Original title: “The clinical relevance of multiple sclerosis genetics: from susceptibility to disease severity and progression.”

melanomaResearch

Data from the ESMO 2026 conference reveals that the combination of the personalized cancer vaccine intismeran autogene and Merck's Keytruda only marginally met analysts' expectations for recurrence-free survival. This raises concerns about its effectiveness in treating tumor types beyond melanoma.

A combination of the personalized cancer vaccine intismeran autogene and Merck's Keytruda just barely cleared analysts’ expectations for recurrence-free survival, leaving questions as to its applicability to tumor types beyond melanoma.

BioSpace·12 days ago·Read at source →

Original title: “ESMO 2026: Merck, Moderna shares fall as cancer vaccine disappoints after data leak”

inherited thyroid metabolism disease inherited glutathione metabolism diseaseResearch

A family's fundraising for gene therapy research pays off : NPR

Gene & Cell Therapy·12 days ago·Read at source →

melanomaResearch

A landmark study shows that the combination of Moderna's cancer vaccine and Merck's Keytruda reduces the risk of relapse or death by 42% in melanoma patients. Despite meeting expectations, the results led to a sell-off in shares of both companies.

A combination of the shot and the immunotherapy Keytruda cut the risk of relapse or death by 42% in a landmark melanoma study that met Wall Street expectations but triggered a “sell-the-news reaction,” one analyst wrote.

BioPharma Dive·12 days ago·Read at source →

Original title: “Moderna, Merck shares fall on eagerly anticipated cancer vaccine results”

Research

Adrenoleukodystrophy (ALD) - Market Insights, Epidemiology, and Market Forecast - 2036 | Newborn Screening and Gene Therapy Unlock 7MM Growth Opportunities

Treatment & Clinical News·12 days ago·Read at source →

intravenous leiomyomatosisResearch

A large cohort study identifies HMGA2 and collagen gene alterations as key drivers in intravenous leiomyomatosis. This research enhances understanding of the disease's genetic underpinnings, potentially guiding future therapeutic strategies.

largest cohort study of intravenous leiomyomatosis reveals hmga2 and collagen gene alterations as cooperative drivers

PubMed Rare Disease·13 days ago·Read at source →

Original title: “The Largest Cohort Study of Intravenous Leiomyomatosis Reveals HMGA2 and Collagen Gene Alterations as Cooperative Drivers.”

Rett syndrome atypical Rett syndromeResearch

Research indicates that degradation of release factor 3 can improve aminoglycoside-mediated translational readthrough at MECP2 nonsense mutations. This finding may have implications for therapeutic strategies targeting mutations associated with Rett syndrome.

release factor 3 degradation enhances aminoglycoside mediated translational readthrough at mecp2 nonsense mutations

PubMed Rare Disease·13 days ago·Read at source →

Original title: “Release factor 3 degradation enhances aminoglycoside-mediated translational readthrough at MECP2 nonsense mutations.”

prostate cancer prostate cancer, hereditary+1 moreResearch

New research identifies circulating immune and cancer driver gene biomarkers that can precede prostate cancer diagnosis by over 10 years. This discovery could enhance early detection strategies for prostate cancer.

circulating immune and cancer driver gene biomarkers precede prostate cancer diagnosis by over 10 yr

PubMed Rare Disease·13 days ago·Read at source →

Original title: “Circulating Immune and Cancer Driver Gene Biomarkers Precede Prostate Cancer Diagnosis by over 10 yr.”

Previous19 / 478Next

Daily Briefings

Not rare diseases news,news about your rare disease.

Earlier

Maxillary sinusitis due to Burkholderia cepacia mimicking fungal sinusitis.

SLC20A2 Intragenic Structural Variants as a Cause of Primary Brain Calcification.

A national multicentre case-control study reveals distinct clinical presentations and prognoses for chronic beryllium disease compared to pulmonary sarcoidosis. This research enhances understanding of these conditions, potentially guiding future treatment approaches.

A recent study identifies rare Malton genotypes of the alpha-1 antitrypsin gene in a multicenter cohort from Southeastern Türkiye. This research enhances understanding of genetic variations associated with alpha-1 antitrypsin deficiency.

A new study highlights the association between pulmonary infiltrates and chronic elevation of blood circulating monocytes. This research could provide insights into underlying mechanisms of respiratory diseases linked to immune system dysregulation.

A case report details an L5 corpectomy performed on a 12-year-old patient due to Rosai-Dorfman disease. This surgical intervention highlights the complexities of managing this rare condition in pediatric patients.

A recent study identifies a correlation between immunoglobulin M levels and the risk of overwhelming post-splenectomy infection in patients with asplenia. This research could inform monitoring strategies for this vulnerable patient population.

Recent studies highlight emerging drugs in phase 2/3 and selected phase 1/2 trials for systemic sclerosis treatment. These developments may offer new therapeutic options for patients suffering from this challenging condition.

A recent study explores how preparation design and connector geometry affect the mechanical properties of additively manufactured periodontal splints. This research could inform future advancements in dental applications and materials.

A recent claims data analysis highlights trends in the epidemiology, healthcare utilization, and disease burden of sickle cell disease in Germany from 2015 to 2024. This study provides valuable insights into the management and impact of the disease in the German healthcare system.

A new study highlights the mechanistic diversity in mitochondrial skeletal disorders, emphasizing that these conditions, while grouped, exhibit significant variability in their underlying mechanisms. This research could inform future therapeutic strategies and patient management.

A recent study highlights the genetic factors influencing multiple sclerosis, linking specific genes to disease susceptibility, severity, and progression. This research could inform future therapeutic strategies and patient management.

Data from the ESMO 2026 conference reveals that the combination of the personalized cancer vaccine intismeran autogene and Merck's Keytruda only marginally met analysts' expectations for recurrence-free survival. This raises concerns about its effectiveness in treating tumor types beyond melanoma.

A family's fundraising for gene therapy research pays off : NPR

A landmark study shows that the combination of Moderna's cancer vaccine and Merck's Keytruda reduces the risk of relapse or death by 42% in melanoma patients. Despite meeting expectations, the results led to a sell-off in shares of both companies.

Adrenoleukodystrophy (ALD) - Market Insights, Epidemiology, and Market Forecast - 2036 | Newborn Screening and Gene Therapy Unlock 7MM Growth Opportunities

A large cohort study identifies HMGA2 and collagen gene alterations as key drivers in intravenous leiomyomatosis. This research enhances understanding of the disease's genetic underpinnings, potentially guiding future therapeutic strategies.

Research indicates that degradation of release factor 3 can improve aminoglycoside-mediated translational readthrough at MECP2 nonsense mutations. This finding may have implications for therapeutic strategies targeting mutations associated with Rett syndrome.

New research identifies circulating immune and cancer driver gene biomarkers that can precede prostate cancer diagnosis by over 10 years. This discovery could enhance early detection strategies for prostate cancer.

Not rare diseases news,
news about your rare disease.