Explore Diseases Find Orgs Patient Assistance News Insights About

Kisho

Kisho is an information platform, not a medical provider. Nothing on this site constitutes medical advice, diagnosis, or treatment recommendations. All content is aggregated from publicly available sources (including ClinicalTrials.gov, PubMed, FDA.gov, and Orphanet) and is provided for informational purposes only. Clinical trial eligibility, treatment decisions, and any health-related actions should always be discussed with a qualified healthcare professional. Kisho does not endorse any specific therapy, organization, or clinical trial. Terms of use · Privacy policy

Open rare disease resources — free, sourced, never gated.

Resources

Rare Disease Directory
Patient Organization Directory
Patient Assistance Programs
Rare Disease News
Clinical Trials
Research Publications

Legal

Privacy Policy
Terms of Service
Accessibility
About & Methodology
Contact

What's new in your rare disease | Kisho

Not rare diseases news,
news about your rare disease.

Every story we pull is tagged to the disease it’s about — so you can filter to your condition and read only what matters.

News sourcesFDA·NIH·CDC·EMA·PubMed·Federal Register·NORD·EURORDIS·Global Genes·The Mighty·BioPharma Dive·BioSpace

Newsroom9,718 Trends

Daily Briefings

20 earlier

Filter & sort

Source

Sort by

Earlier

20 stories

Research

Leveraging Prior Knowledge in the Development of Human Gene Therapy Products Incorporating Genome Editing; Draft Guidance for Industry; Availability

Federal Register - HHS·5 months ago·Read at source →

Research

Clinical pharmacology insights from recent cell and gene therapy approvals relevant to pediatrics.

PubMed Rare Disease·5 months ago·Read at source →

Research

Research explores the potential therapeutic effects of V1a receptor antagonism in treating circadian disorders. This study provides insights into the mechanisms that could lead to new treatment options for patients affected by these conditions.

modelling the effect of v1a receptor antagonism and its potential therapeutic effect in circadian disorders

PubMed Rare Disease·5 months ago·Read at source →

Original title: “Modelling the effect of V1a receptor antagonism and its potential therapeutic effect in circadian disorders.”

ataxia telangiectasia ataxia - telangiectasia variantResearch

The Ataxia Global Initiative's MRI Biomarkers Working Group has published recommendations for MRI end-points in clinical trials for ataxias. These guidelines aim to standardize the use of MRI as a biomarker in research, potentially enhancing the development of therapies for these conditions.

mri end points for clinical trials in ataxias recommendations from the ataxia global initiative mri biomarkers working group

PubMed Rare Disease·5 months ago·Read at source →

Original title: “MRI end-points for clinical trials in ataxias: recommendations from the Ataxia Global Initiative MRI Biomarkers Working Group.”

phyllodes tumor benign phyllodes tumor+1 moreResearch

A rare case study highlights malignant transformation in bilateral phyllodes tumor, resulting in osteosarcomatous metastases. This finding contributes to the understanding of tumor behavior and potential treatment implications.

rare case of malignant transformation in bilateral phyllodes tumor leading to osteosarcomatous metastases

PubMed Rare Disease·5 months ago·Read at source →

Original title: “A Rare Case of Malignant Transformation in Bilateral Phyllodes Tumor Leading to Osteosarcomatous Metastases.”

acquired polycythemia veraResearch

A systematic literature review highlights the burden of thromboembolism and disease progression in polycythemia vera patients in the United States. The findings underscore the need for improved management strategies for this rare blood disorder.

burden of thromboembolism disease progression and phlebotomy among polycythemia vera patients in the united states a systematic literature review

PubMed Rare Disease·5 months ago·Read at source →

Original title: “Burden of thromboembolism, disease progression, and phlebotomy among polycythemia vera patients in the United States: a systematic literature review.”

Research

A recent study explores the expansion of pathogens and the restoration of the human skin microbiome in patients with CD4 T-cell lymphopenia. This research highlights the complex interactions between immune deficiency and microbial communities.

expansion of pathogens and restoration of human skin microbiome in cd4 t cell lymphopenia

PubMed Rare Disease·5 months ago·Read at source →

Original title: “Expansion of pathogens and restoration of human skin microbiome in CD4 T-cell lymphopenia.”

Research

A recent study explores the pathogenesis of indium lung diseases in rats exposed to indium-tin oxide nanoparticles. This research provides insights into the potential health impacts of these materials, which may inform future studies and regulatory considerations.

pathology illustrates pathogenesis of indium lung diseases in rats induced by indium tin oxide nanoparticles

PubMed Rare Disease·5 months ago·Read at source →

Original title: “Pathology illustrates pathogenesis of indium lung diseases in rats induced by indium-tin oxide nanoparticles.”

aortic dissection lentiginosis aortic aneurysm+1 moreResearch

A recent study presents a single-stage surgical approach for repairing complex congenital aortic arch pathology in adults, addressing dissection and aneurysm. This research could influence future surgical techniques and patient outcomes in this rare condition.

single stage repair of complex congenital aortic arch pathology with dissection and aneurysm in an adult

PubMed Rare Disease·5 months ago·Read at source →

Original title: “Single-Stage Repair of Complex Congenital Aortic Arch Pathology With Dissection and Aneurysm in an Adult.”

infective endocarditis candidemiaResearch

A case study highlights the successful conservative treatment of MRSA-associated infective endocarditis alongside candidemia in a hemodialysis patient. This research contributes to understanding treatment options for complex infections in vulnerable populations.

successful conservative treatment of mrsa associated infective endocarditis with concurrent candidemia in a hemodialysis patient

PubMed Rare Disease·5 months ago·Read at source →

Original title: “Successful conservative treatment of MRSA-associated infective endocarditis with concurrent candidemia in a hemodialysis patient.”

Research

A case-based review explores the complex interactions between Whipple's endocarditis and biologic response modifiers. This study provides insights into the host-pathogen dynamics, which could inform future therapeutic strategies.

whipple s endocarditis and biologic response modifiers a case based review of an intricate host pathogen interaction

PubMed Rare Disease·5 months ago·Read at source →

Original title: “Whipple's endocarditis and biologic response modifiers: a case-based review of an intricate host-pathogen interaction.”

parotid gland squamous cell carcinoma parotid gland carcinoma ex pleomorphic adenoma+1 moreResearch

A population-based study investigates the prognosis of T4b parotid gland squamous cell carcinoma, providing valuable insights into patient outcomes. This research contributes to the understanding of this rare cancer type.

prognosis of t4b parotid gland squamous cell carcinoma a population based study

PubMed Rare Disease·5 months ago·Read at source →

Original title: “Prognosis of T4b parotid gland squamous cell carcinoma: a population-based study.”

inborn error of immunity inborn errors of metabolism+1 moreResearch

The Primary Immune Deficiency Treatment Consortium (PIDTC) has launched the IMPACT study to monitor immune responses and clinical trajectories in patients with inborn errors of immunity. This initiative aims to enhance understanding and treatment of primary immune deficiencies.

impact immune monitoring and phenotype assessment of clinical trajectory for patients with inborn errors of immunity from the primary immune deficiency treatment consortium pidtc

PubMed Rare Disease·5 months ago·Read at source →

Original title: “IMPACT (Immune Monitoring and Phenotype Assessment of Clinical Trajectory) for Patients with Inborn Errors of Immunity from the Primary Immune Deficiency Treatment Consortium (PIDTC).”

Research

A new publication discusses advancements in mRNA therapeutics, highlighting potential applications in rare diseases. The research outlines innovative strategies that could enhance the efficacy and delivery of mRNA-based treatments.

towards mrna therapeutics 2 0

PubMed Rare Disease·5 months ago·Read at source →

Original title: “Towards mRNA therapeutics 2.0.”

aortic aneurysm, familial thoracic 8 aortic aneurysm, familial thoracic 6Research

A study published in PubMed reveals the genetic yield of targeted diagnostic screening in 368 patients with thoracic aortic dissection. This research enhances understanding of the genetic factors involved in this condition.

genetic yield of targeted diagnostic screening in a large european cohort of 368 thoracic aortic dissection patients

PubMed Rare Disease·5 months ago·Read at source →

Original title: “Genetic yield of targeted diagnostic screening in a large European cohort of 368 thoracic aortic dissection patients.”

angioimmunoblastic T-cell lymphoma Burkitt lymphoma+1 moreResearch

A recent study reveals a shared clonal origin between angioimmunoblastic T-cell lymphoma and Burkitt lymphoma, suggesting they evolve from a common precursor. This discovery may enhance understanding of the genetic mechanisms underlying these lymphomas.

shared clonal origin of angioimmunoblastic t cell lymphoma and burkitt lymphoma arising through divergent evolution from a common precursor

PubMed Rare Disease·5 months ago·Read at source →

Original title: “Shared clonal origin of angioimmunoblastic T-cell lymphoma and Burkitt lymphoma arising through divergent evolution from a common precursor.”

Research

A retrospective bicentric study analyzes the outcomes of operative and antibiotic treatments for cervical spondylodiscitis. The findings contribute to understanding effective management strategies for this rare condition.

operative and antibiotic treatment of cervical spondylodiscitis a retrospective bicentric outcome analysis

PubMed Rare Disease·5 months ago·Read at source →

Original title: “Operative and antibiotic treatment of cervical spondylodiscitis: a retrospective bicentric outcome analysis.”

Research

Research highlights the essential role of HSD17B7 in the function of sensory hair cells through its regulation of cholesterol synthesis. This discovery may have implications for understanding hearing loss mechanisms.

hsd17b7 is required for the function of sensory hair cells by regulating cholesterol synthesis

PubMed Rare Disease·5 months ago·Read at source →

Original title: “HSD17B7 is required for the function of sensory hair cells by regulating cholesterol synthesis.”

chest wall lipoma chest wall bone cancer+1 moreResearch

A case report details a rare instance of cytokeratin-positive pleomorphic chest wall sarcoma that mimicked malignant peripheral nerve sheath tumor (MPNST). This discovery may enhance diagnostic accuracy for similar sarcomas.

cytokeratin positive pleomorphic chest wall sarcoma mimicking mpnst a case report

PubMed Rare Disease·5 months ago·Read at source →

Original title: “Cytokeratin-Positive Pleomorphic Chest Wall Sarcoma Mimicking MPNST: A Case Report.”

Research

A recent study highlights the diagnostic challenges of extranodal Rosai-Dorfman disease with bilateral renal involvement. This research underscores the complexity of identifying this rare condition, which may lead to misdiagnosis.

extranodal rosai dorfman disease with bilateral renal involvement a diagnostic challenge

PubMed Rare Disease·5 months ago·Read at source →

Original title: “Extranodal Rosai-Dorfman disease with bilateral renal involvement: A diagnostic challenge.”

Previous265 / 486Next

Daily Briefings

Not rare diseases news,news about your rare disease.

Earlier

Leveraging Prior Knowledge in the Development of Human Gene Therapy Products Incorporating Genome Editing; Draft Guidance for Industry; Availability

Clinical pharmacology insights from recent cell and gene therapy approvals relevant to pediatrics.

Research explores the potential therapeutic effects of V1a receptor antagonism in treating circadian disorders. This study provides insights into the mechanisms that could lead to new treatment options for patients affected by these conditions.

The Ataxia Global Initiative's MRI Biomarkers Working Group has published recommendations for MRI end-points in clinical trials for ataxias. These guidelines aim to standardize the use of MRI as a biomarker in research, potentially enhancing the development of therapies for these conditions.

A rare case study highlights malignant transformation in bilateral phyllodes tumor, resulting in osteosarcomatous metastases. This finding contributes to the understanding of tumor behavior and potential treatment implications.

A systematic literature review highlights the burden of thromboembolism and disease progression in polycythemia vera patients in the United States. The findings underscore the need for improved management strategies for this rare blood disorder.

A recent study explores the expansion of pathogens and the restoration of the human skin microbiome in patients with CD4 T-cell lymphopenia. This research highlights the complex interactions between immune deficiency and microbial communities.

A recent study explores the pathogenesis of indium lung diseases in rats exposed to indium-tin oxide nanoparticles. This research provides insights into the potential health impacts of these materials, which may inform future studies and regulatory considerations.

A recent study presents a single-stage surgical approach for repairing complex congenital aortic arch pathology in adults, addressing dissection and aneurysm. This research could influence future surgical techniques and patient outcomes in this rare condition.

A case study highlights the successful conservative treatment of MRSA-associated infective endocarditis alongside candidemia in a hemodialysis patient. This research contributes to understanding treatment options for complex infections in vulnerable populations.

A case-based review explores the complex interactions between Whipple's endocarditis and biologic response modifiers. This study provides insights into the host-pathogen dynamics, which could inform future therapeutic strategies.

A population-based study investigates the prognosis of T4b parotid gland squamous cell carcinoma, providing valuable insights into patient outcomes. This research contributes to the understanding of this rare cancer type.

The Primary Immune Deficiency Treatment Consortium (PIDTC) has launched the IMPACT study to monitor immune responses and clinical trajectories in patients with inborn errors of immunity. This initiative aims to enhance understanding and treatment of primary immune deficiencies.

A new publication discusses advancements in mRNA therapeutics, highlighting potential applications in rare diseases. The research outlines innovative strategies that could enhance the efficacy and delivery of mRNA-based treatments.

A study published in PubMed reveals the genetic yield of targeted diagnostic screening in 368 patients with thoracic aortic dissection. This research enhances understanding of the genetic factors involved in this condition.

A recent study reveals a shared clonal origin between angioimmunoblastic T-cell lymphoma and Burkitt lymphoma, suggesting they evolve from a common precursor. This discovery may enhance understanding of the genetic mechanisms underlying these lymphomas.

A retrospective bicentric study analyzes the outcomes of operative and antibiotic treatments for cervical spondylodiscitis. The findings contribute to understanding effective management strategies for this rare condition.

Research highlights the essential role of HSD17B7 in the function of sensory hair cells through its regulation of cholesterol synthesis. This discovery may have implications for understanding hearing loss mechanisms.

A case report details a rare instance of cytokeratin-positive pleomorphic chest wall sarcoma that mimicked malignant peripheral nerve sheath tumor (MPNST). This discovery may enhance diagnostic accuracy for similar sarcomas.

A recent study highlights the diagnostic challenges of extranodal Rosai-Dorfman disease with bilateral renal involvement. This research underscores the complexity of identifying this rare condition, which may lead to misdiagnosis.

Not rare diseases news,
news about your rare disease.