Marked racial and socioeconomic disparities significantly influence survival outcomes in patients with PCNSL across the US population. With a strong background in biomedical science and genetics, Dr Garlapow has held key roles in medical education and clinical genetics and genomics, where she honed her skills in developing strategic proposals, securing funding, delivering high-quality educational content, and composing engaging medical journalism pieces. This article originally appeared on Rare Disease Advisor. ... Maqbool S, Rehman MEU, Tahir R, et al. Unraveling survival disparities in primary central nervous system (CNS) lymphoma: an analysis of race, socioeconomic factors, and treatment outcomes using the surveillance, epidemiology, and end results program (2000-2021). “The survival gap between population-level outcomes and clinical trial results reflects systemic barriers to care, treatment heterogeneity, and limitations of current approaches,” stated the authors. “Urgent action is needed at clinical, policy, and research levels to ensure equitable access to evidence-based therapies including HDMTX-based chemoimmunotherapy strategies, consolidation programs with either AutoHCT or radiation therapy given by appropriately trained personnel, accelerate integration of novel agents such as CAR-T and targeted agents, and address structural inequities that continue to shape survival in PCNSL.” We want you to take advantage of everything Cancer Therapy Advisor has to offer. To view unlimited content, log in or register for free. ... Register now at no charge to access unlimited clinical news, full-length features, case studies, conference coverage, and more. The cohort had a mean age of 63 (±15) years, and 52.3% were male. Racial distribution included 63.9% White, 16.0% Hispanic, 12.2% Asian or Pacific Islander, 7.3% African American, and 0.4% Native American or Alaskan Native. Treatment exposure included chemotherapy in 64.3% and radiation therapy in 27.3%.

Original title: “Racial and Socioeconomic Disparities Shape Survival in PCNSL - Cancer Therapy Advisor”

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